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https://hdl.handle.net/10356/137605| Title: | An oxaliplatin(IV) prodrug-based supramolecular self-delivery nanocarrier for targeted colorectal cancer treatment | Authors: | Lim, Wei Qi Phua, Fiona Soo Zeng Chen, Hongzhong Zhao, Yanli |
Keywords: | Science::Chemistry | Issue Date: | 2018 | Source: | Lim, W. Q., Phua, F. S. Z., Chen, H., & Zhao, Y. (2018). An oxaliplatin(IV) prodrug-based supramolecular self-delivery nanocarrier for targeted colorectal cancer treatment. Chemical Communications, 54, 12762-12765. doi:10.1039/c8cc07858k | Journal: | Chemical Communications | Abstract: | A redox-responsive supramolecular nanocarrier was constructed from the self-assembly of spermine modified cyclodextrin and oxaliplatin prodrug. The nanocarrier could preferentially accumulate in polyamine transporter over-expressing HCT116 cells, releasing drugs under a reducing intracellular environment to maximize anticancer treatment. | URI: | https://hdl.handle.net/10356/137605 | ISSN: | 1359-7345 | DOI: | 10.1039/c8cc07858k | Rights: | © 2018 The Author(s) (Royal Society of Chemistry). All rights reserved. This paper was published in Chemical Communications and is made available with permission of The Author(s) (Royal Society of Chemistry). | Fulltext Permission: | open | Fulltext Availability: | With Fulltext |
| Appears in Collections: | SPMS Journal Articles |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| c8cc07858k.pdf | 1.03 MB | Adobe PDF | View/Open |
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