Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/137763
Title: Carbene-catalyzed α-carbon amination of chloroaldehydes for enantioselective access to dihydroquinoxaline derivatives
Authors: Huang, Ruoyan
Chen, Xingkuan
Mou, Chengli
Luo, Guoyong
Li, Yongjia
Li, Xiangyang
Xue, Wei
Jin, Zhichao
Chi, Robin Yonggui
Keywords: Science::Chemistry::Organic chemistry
Issue Date: 2019
Source: Huang, R., Chen, X., Mou, C., Luo, G., Li, Y., Li, X., … Chi, R. Y. (2019). Carbene-catalyzed α-carbon amination of chloroaldehydes for enantioselective access to dihydroquinoxaline derivatives. Organic Letters, 21(11), 4340-4344. doi:10.1021/acs.orglett.9b01520
Journal: Organic Letters
Abstract: An NHC-catalyzed α-carbon amination of chloroaldehydes was developed. Cyclohexadiene-1,2-diimines are used as amination reagents and four-atom synthons. Our reaction affords optically enriched dihydroquinoxalines that are core structures in natural products and synthetic bioactive molecules.
URI: https://hdl.handle.net/10356/137763
ISSN: 1523-7060
DOI: 10.1021/acs.orglett.9b01520
Schools: School of Physical and Mathematical Sciences 
Rights: This document is the Accepted Manuscript version of a Published Work that appeared in final form in Organic Letters, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acs.orglett.9b01520
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:SPMS Journal Articles

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