Please use this identifier to cite or link to this item:
Title: Combinatorial nano-bio interfaces
Authors: Cai, Pingqiang
Zhang, Xiaoqian
Wang, Ming
Wu, Yun-Long
Chen, Xiaodong
Keywords: Engineering::Materials
Issue Date: 2018
Source: Cai, P., Zhang, X., Wang, M., Wu, Y.-L., & Chen, X. (2018). Combinatorial nano-bio interfaces. ACS nano, 12(6), 5078-5084. doi:10.1021/acsnano.8b03285
Journal: ACS nano
Abstract: Nano-bio interfaces are emerging from the convergence of engineered nanomaterials and biological entities. Despite rapid growth, clinical translation of biomedical nanomaterials is heavily compromised by the lack of comprehensive understanding of biophysicochemical interactions at nano-bio interfaces. In the past decade, a few investigations have adopted a combinatorial approach toward decoding nano-bio interfaces. Combinatorial nano-bio interfaces comprise the design of nanocombinatorial libraries and high-throughput bioevaluation. In this Perspective, we address challenges in combinatorial nano-bio interfaces and call for multiparametric nanocombinatorics (composition, morphology, mechanics, surface chemistry), multiscale bioevaluation (biomolecules, organelles, cells, tissues/organs), and the recruitment of computational modeling and artificial intelligence. Leveraging combinatorial nano-bio interfaces will shed light on precision nanomedicine and its potential applications.
ISSN: 1936-0851
DOI: 10.1021/acsnano.8b03285
Schools: School of Materials Science & Engineering 
Organisations: Innovative Center for Flexible Devices
Rights: © 2018 American Chemical Society. All rights reserved. This paper was published in ACS Nano and is made available with permission of American Chemical Society.
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:MSE Journal Articles

Files in This Item:
File Description SizeFormat 
Perspective_Combinatorial Nanobiointerfaces .pdf5.67 MBAdobe PDFView/Open

Citations 5

Updated on Jun 3, 2023

Web of ScienceTM
Citations 5

Updated on Jun 1, 2023

Page view(s)

Updated on Jun 6, 2023

Download(s) 20

Updated on Jun 6, 2023

Google ScholarTM




Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.