Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/137812
Title: Tactile chemomechanical transduction based on an elastic microstructured array to enhance the sensitivity of portable biosensors
Authors: Wang, Ting
Qi, Dianpeng
Yang, Hui
Liu, Zhiyuan
Wang, Ming
Leow, Wan Ru
Chen, Geng
Yu, Jiancan
He, Ke
Cheng, Hongwei
Wu, Yun-Long
Zhang, Han
Chen, Xiaodong
Keywords: Engineering::Materials
Issue Date: 2018
Source: Wang, T., Qi, D., Yang, H., Liu, Z., Wang, M., Leow, W. R., . . . Chen, X. (2019). Tactile chemomechanical transduction based on an elastic microstructured array to enhance the sensitivity of portable biosensors. Advanced Materials, 31(1), 1803883-. doi:10.1002/adma.201803883
Journal: Advanced Materials
Abstract: Tactile sensors capable of perceiving biophysical signals such as force, pressure, or strain have attracted extensive interest for versatile applications in electronic skin, noninvasive healthcare, and biomimetic prostheses. Despite these great achievements, they are still incapable of detecting bio/chemical signals that provide even more meaningful and precise health information due to the lack of efficient transduction principles. Herein, a tactile chemomechanical transduction strategy that enables the tactile sensor to perceive bio/chemical signals is proposed. In this methodology, pyramidal tactile sensors are linked with biomarker‐induced gas‐producing reactions, which transduce biomarker signals to electrical signals in real time. The method is advantageous as it enhances electrical signals by more than tenfold based on a triple‐step signal amplification strategy, as compared to traditional electrical biosensors. It also constitutes a portable and general platform capable of quantifying a wide spectrum of targets including carcinoembryonic antigen, interferon‐γ, and adenosine. Such tactile chemomechanical transduction would greatly broaden the application of tactile sensors toward bio/chemical signals perception which can be used in ultrasensitive portable biosensors and chemical‐responsive chemomechanical systems.
URI: https://hdl.handle.net/10356/137812
ISSN: 0935-9648
DOI: 10.1002/adma.201803883
Rights: This is the peer reviewed version of the following article: Wang, T., Qi, D., Yang, H., Liu, Z., Wang, M., Leow, W. R., . . . Chen, X. (2019). Tactile chemomechanical transduction based on an elastic microstructured array to enhance the sensitivity of portable biosensors. Advanced Materials, 31(1), 1803883-. doi:10.1002/adma.201803883, which has been published in final form at https://doi.org/10.1002/adma.201803883. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:MSE Journal Articles

SCOPUSTM   
Citations

21
Updated on Jun 18, 2020

PublonsTM
Citations 50

24
Updated on Nov 21, 2020

Page view(s) 50

41
Updated on Nov 24, 2020

Download(s) 50

7
Updated on Nov 24, 2020

Google ScholarTM

Check

Altmetric


Plumx

Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.