Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/138027
Title: Omega-3 (ω-3) and social skills interventions for reactive aggression and childhood externalizing behavior problems : a randomized, stratified, double-blind, placebo-controlled, factorial trial
Authors: Raine, Adrian
Ang, Rebecca P.
Choy, Olivia
Hibbeln, Joseph R.
Ho, Ringo M.-H.
Lim, Choon Guan
Lim-Ashworth, Nikki S. J.
Ling, Shichun
Liu, Jean C. J.
Ooi, Yoon Phaik
Tan, Yi Ren
Fung, Daniel S. S.
Keywords: Social sciences::Psychology
Issue Date: 2019
Source: Raine, A., Ang, R. P., Choy, O., Hibbein, J. R., Ho, R. M.-H., Lim, C. G., . . ., Fung, D. S. S. (2019). Omega-3 (ω-3) and social skills interventions for reactive aggression and childhood externalizing behavior problems: a randomized, stratified, double-blind, placebo-controlled, factorial trial. Psychological medicine, 49(2), 335-344. doi:10.1017/S0033291718000983
Journal: Psychological medicine
Abstract: Background:While studies suggest that nutritional supplementation may reduce aggressive behavior in children, few have examined their effects on specific forms of aggression. This study tests the primary hypothesis that omega-3 (ω-3), both alone and in conjunction with social skills training, will have particular post-treatment efficacy for reducing childhood reactive aggression relative to baseline. Methods:In this randomized, double-blind, stratified, placebo-controlled, factorial trial, a clinical sample of 282 children with externalizing behavior aged 7–16 years was randomized into ω-3 only, social skills only, ω-3 + social skills, and placebo control groups. Treatment duration was 6 months. The primary outcome measure was reactive aggression collected at 0, 3, 6, 9, and 12 months, with antisocial behavior as a secondary outcome. Results:Children in the ω-3-only group showed a short-term reduction (at 3 and 6 months) in self-report reactive aggression, and also a short-term reduction in overall antisocial behavior. Sensitivity analyses and a robustness check replicated significant interaction effects. Effect sizes (d) were small, ranging from 0.17 to 0.31. Conclusions:Findings provide some initial support for the efficacy of ω-3 in reducing reactive aggression over and above standard care (medication and parent training), but yield only preliminary and limited support for the efficacy of ω-3 in reducing overall externalizing behavior in children. Future studies could test further whether ω-3 shows promise in reducing more reactive, impulsive forms of aggression.
URI: https://hdl.handle.net/10356/138027
ISSN: 0033-2917
DOI: 10.1017/S0033291718000983
Rights: © 2018 Cambridge University Press. All rights reserved.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:SSS Journal Articles

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