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https://hdl.handle.net/10356/138240
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Liu, Bin | en_US |
dc.contributor.author | Yan, Jiekuan | en_US |
dc.contributor.author | Huang, Ruoyan | en_US |
dc.contributor.author | Wang, Weihong | en_US |
dc.contributor.author | Jin, Zhichao | en_US |
dc.contributor.author | Zanoni, Giuseppe | en_US |
dc.contributor.author | Zheng, Pengcheng | en_US |
dc.contributor.author | Yang, Song | en_US |
dc.contributor.author | Chi, Robin Yonggui | en_US |
dc.date.accessioned | 2020-04-29T08:12:39Z | - |
dc.date.available | 2020-04-29T08:12:39Z | - |
dc.date.issued | 2018 | - |
dc.identifier.citation | Liu, B., Yan, K., Huang, R., Wang, W., Jin, Z, Zanoni, G., . . ., Chi, R. Y. (2018). Kinetic resolution of 1,2-diols via NHC-catalyzed site-selective esterification. Organic letters, 20(12), 3447-3450. doi:10.1021/acs.orglett.8b01029 | en_US |
dc.identifier.issn | 1523-7052 | en_US |
dc.identifier.uri | https://hdl.handle.net/10356/138240 | - |
dc.description.abstract | A kinetic resolution of 1,2-diols bearing both a secondary and a primary alcohol motif through an N-heterocyclic carbene-catalyzed oxidative acylation reaction has been developed. A site- and enantioselective esterification reaction is involved for this process. Both the monoacylated diols obtained and the remaining enantioenriched 1,2-diols are versatile building blocks for the preparation of functional molecules with proven biological activities. | en_US |
dc.description.sponsorship | NRF (Natl Research Foundation, S’pore) | en_US |
dc.description.sponsorship | ASTAR (Agency for Sci., Tech. and Research, S’pore) | en_US |
dc.description.sponsorship | MOE (Min. of Education, S’pore) | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | Organic letters | en_US |
dc.rights | © 2018 American Chemical Society. All rights reserved. This paper was published in Organic letters and is made available with permission of American Chemical Society. | en_US |
dc.subject | Science::Chemistry::Organic chemistry | en_US |
dc.title | Kinetic resolution of 1,2-diols via NHC-catalyzed site-selective esterification | en_US |
dc.type | Journal Article | en |
dc.contributor.school | School of Physical and Mathematical Sciences | en_US |
dc.identifier.doi | 10.1021/acs.orglett.8b01029 | - |
dc.description.version | Accepted version | en_US |
dc.identifier.pmid | 29863883 | - |
dc.identifier.scopus | 2-s2.0-85048787588 | - |
dc.identifier.issue | 12 | en_US |
dc.identifier.volume | 20 | en_US |
dc.identifier.spage | 3447 | en_US |
dc.identifier.epage | 3450 | en_US |
dc.subject.keywords | Enantioselective | en_US |
dc.subject.keywords | Esterification | en_US |
item.grantfulltext | open | - |
item.fulltext | With Fulltext | - |
Appears in Collections: | SPMS Journal Articles |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Kinetic Resolution of 1,2-Diols via NHC-Catalyzed Site-Selective Esterification.pdf | 1.09 MB | Adobe PDF | View/Open |
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