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Title: Spatially controlled molecular encapsulation in natural pine pollen microcapsules
Authors: Prabhakar, Arun Kumar
Potroz, Michael G.
Park, Soohyun
Miyako, Eijiro
Cho, Nam-Joon
Keywords: Engineering::Materials
Issue Date: 2018
Source: Prabhakar, A. K., Potroz, M. G., Park, S., Miyako, E., & Cho, N.-J. (2018). Spatially controlled molecular encapsulation in natural pine pollen microcapsules. Particle and Particle Systems Characterization, 35, 1800151-. doi:10.1002/ppsc.201800151
Journal: Particle and Particle Systems Characterization
Abstract: The loading of multiple drugs into a single carrier is an effective advanced clinical therapeutic for various diseases. Here, by exploiting the architectural features of natural pine pollen from Pinus massoniana, the spatially controlled encapsulation of two types of molecules in distinct compartments of a single microparticulate carrier is demonstrated. By simple vacuum and passive loading, diverse molecules such as proteins, organic dyes, and a drug are effectively encapsulated into the pollen microcapsule in binary fashion. This technique represents an advancement toward the use of natural pollen grains as a multifunctional molecular vehicle for functional drug delivery systems and innovative theranostic microdevices.
ISSN: 0934-0866
DOI: 10.1002/ppsc.201800151
Rights: © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. All rights reserved. This paper was published in Particle and Particle Systems Characterization and is made available with permission of WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:MSE Journal Articles

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