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Title: Supramolecular vesicles for stimulus-responsive drug delivery
Authors: Xing, Pengyao
Zhao, Yanli
Keywords: Science::Medicine
Issue Date: 2018
Source: Xing, P., & Zhao, Y. (2018). Supramolecular vesicles for stimulus-responsive drug delivery. Small Methods, 2(4), 1700364-. doi:10.1002/smtd.201700364
Journal: Small Methods
Abstract: Developing smart controlled‐release systems for cancer therapy is highly desired in biomedicine. In order to improve therapeutic efficacy and lower undesired side effects, the construction of stimulus‐responsive nanocarriers is a favorable solution. Emerging supramolecular self‐assemblies possessing intrinsic dynamic and adaptive features present promising capabilities for the fabrication of stimulus‐responsive drug‐release systems. Dynamic supramolecular vesicles have attracted considerable attention as therapeutic carriers ascribed to their advantages of high‐cargo‐loading capacity/feasibility, excellent biocompatibility, and facile functionalization. Here, a summary and discussion of recent significant development of vesicles constructed by supramolecular self‐assembly for stimulus‐responsive drug delivery and therapeutics is given. Through presenting some representative studies, strategies regarding the design, synthesis, characterization, and biomedical applications of supramolecular vesicle carriers are highlighted according to various stimulus triggers. The aim is to provide a quick research update in this rapidly developing field.
ISSN: 2366-9608
DOI: 10.1002/smtd.201700364
Rights: © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. All rights reserved.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:SPMS Journal Articles

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