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DC Field | Value | Language |
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dc.contributor.author | Evangelou, Evangelos | en_US |
dc.contributor.author | Warren, Helen R. | en_US |
dc.contributor.author | Mosen-Ansorena, David | en_US |
dc.contributor.author | Mifsud, Borbala | en_US |
dc.contributor.author | Pazoki, Raha | en_US |
dc.contributor.author | Gao, He | en_US |
dc.contributor.author | Ntritsos, Georgios | en_US |
dc.contributor.author | Dimou, Niki | en_US |
dc.contributor.author | Cabrera, Claudia P. | en_US |
dc.contributor.author | Ibrahim Karaman | en_US |
dc.contributor.author | Ng, Fu Liang | en_US |
dc.contributor.author | Evangelou, Marina | en_US |
dc.contributor.author | Witkowska, Katarzyna | en_US |
dc.contributor.author | Tzanis, Evan | en_US |
dc.contributor.author | Hellwege, Jacklyn N. | en_US |
dc.contributor.author | Giri, Ayush | en_US |
dc.contributor.author | Edwards, Digna R. Velez | en_US |
dc.contributor.author | Sun, Yan V. | en_US |
dc.contributor.author | Cho, Kelly | en_US |
dc.contributor.author | Gaziano, J. Michael | en_US |
dc.contributor.author | Wilson, Peter W. F. | en_US |
dc.contributor.author | Tsao, Philip S. | en_US |
dc.contributor.author | Kovesdy, Csaba P. | en_US |
dc.contributor.author | Esko, Tonu | en_US |
dc.contributor.author | Mägi, Reedik | en_US |
dc.contributor.author | Milani, Lili | en_US |
dc.contributor.author | Almgren, Peter | en_US |
dc.contributor.author | Boutin, Thibaud | en_US |
dc.contributor.author | Debette, Stéphanie | en_US |
dc.contributor.author | Ding, Jun | en_US |
dc.contributor.author | Giulianini, Franco | en_US |
dc.contributor.author | Holliday, Elizabeth G. | en_US |
dc.contributor.author | Jackson, Anne U. | en_US |
dc.contributor.author | Li-Gao, Ruifang | en_US |
dc.contributor.author | Lin, Wei-Yu | en_US |
dc.contributor.author | Luan, Jian'an | en_US |
dc.contributor.author | Mangino, Massimo | en_US |
dc.contributor.author | Oldmeadow, Christopher | en_US |
dc.contributor.author | Prins, Bram Peter | en_US |
dc.contributor.author | Qian, Yong | en_US |
dc.contributor.author | Sargurupremraj, Muralidharan | en_US |
dc.contributor.author | Shah, Nabi | en_US |
dc.contributor.author | Surendran, Praveen | en_US |
dc.contributor.author | Thériault, Sébastien | en_US |
dc.contributor.author | Verweij, Niek | en_US |
dc.contributor.author | Willems, Sara M. | en_US |
dc.contributor.author | Zhao, Jing-Hua | en_US |
dc.contributor.author | Amouyel, Philippe | en_US |
dc.contributor.author | Connell, John | en_US |
dc.contributor.author | de Mutsert, Renée | en_US |
dc.contributor.author | Doney, Alex S. F. | en_US |
dc.contributor.author | Farrall, Martin | en_US |
dc.contributor.author | Menni, Cristina | en_US |
dc.contributor.author | Morris, Andrew D. | en_US |
dc.contributor.author | Raymond Noordam | en_US |
dc.contributor.author | Paré, Guillaume | en_US |
dc.contributor.author | Poulter, Neil R. | en_US |
dc.contributor.author | Shields, Denis C. | en_US |
dc.contributor.author | Stanton, Alice | en_US |
dc.contributor.author | Thom, Simon | en_US |
dc.contributor.author | Abecasis, Gonçalo | en_US |
dc.contributor.author | Najaf Amin | en_US |
dc.contributor.author | Arking, Dan E. | en_US |
dc.contributor.author | Ayers, Kristin L. | en_US |
dc.contributor.author | Barbieri, Caterina M. | en_US |
dc.contributor.author | Batini, Chiara | en_US |
dc.contributor.author | Bis, Joshua C. M. | en_US |
dc.contributor.author | Blake, Tineka | en_US |
dc.contributor.author | Bochud, Murielle | en_US |
dc.contributor.author | Boehnke, Michael | en_US |
dc.contributor.author | Boerwinkle, Eric | en_US |
dc.contributor.author | Boomsma, Dorret I. | en_US |
dc.contributor.author | Bottinger, Erwin P. | en_US |
dc.contributor.author | Braund, Peter S. | en_US |
dc.contributor.author | Brumat, Marco | en_US |
dc.contributor.author | Campbell, Archie | en_US |
dc.contributor.author | Campbell, Harry | en_US |
dc.contributor.author | Chakravarti, Aravinda | en_US |
dc.contributor.author | Chambers, John Campbell | en_US |
dc.contributor.author | Chauhan, Ganesh | en_US |
dc.contributor.author | Ciullo, Marina | en_US |
dc.contributor.author | Cocca, Massimiliano | en_US |
dc.contributor.author | Collins, Francis | en_US |
dc.contributor.author | Cordell, Heather J. | en_US |
dc.contributor.author | Davies, Gail | en_US |
dc.contributor.author | de Borst, Martin H. | en_US |
dc.contributor.author | de Geus, Eco J. | en_US |
dc.contributor.author | Deary, Ian J. | en_US |
dc.contributor.author | Deelen, Joris | en_US |
dc.contributor.author | Del Greco M., Fabiola | en_US |
dc.contributor.author | Demirkale, Cumhur Yusuf | en_US |
dc.contributor.author | Dörr, Marcus | en_US |
dc.contributor.author | Ehret, Georg B. | en_US |
dc.contributor.author | Elosua, Roberto | en_US |
dc.contributor.author | Enroth, Stefan | en_US |
dc.contributor.author | Erzurumluoglu, A. Mesut | en_US |
dc.contributor.author | Ferreira, Teresa | en_US |
dc.contributor.author | Frånberg, Mattias | en_US |
dc.contributor.author | Franco, Oscar H. | en_US |
dc.contributor.author | Gandin, Ilaria | en_US |
dc.contributor.author | Gasparini, Paolo | en_US |
dc.contributor.author | Giedraitis, Vilmantas | en_US |
dc.contributor.author | Gieger, Christian | en_US |
dc.contributor.author | Girotto, Giorgia | en_US |
dc.contributor.author | Goel, Anuj | en_US |
dc.contributor.author | Gow, Alan J. | en_US |
dc.contributor.author | Gudnason, Vilmundur | en_US |
dc.contributor.author | Guo, Xiuqing | en_US |
dc.contributor.author | Gyllensten, Ulf | en_US |
dc.contributor.author | Hamsten, Anders | en_US |
dc.contributor.author | Harris, Tamara B. | en_US |
dc.contributor.author | Harris, Sarah E. | en_US |
dc.contributor.author | Hartman, Catharina A. | en_US |
dc.contributor.author | Havulinna, Aki S. | en_US |
dc.contributor.author | Hicks, Andrew A. | en_US |
dc.contributor.author | Hofer, Edith | en_US |
dc.contributor.author | Hofman, Albert | en_US |
dc.contributor.author | Hottenga, Jouke-Jan | en_US |
dc.contributor.author | Huffman, Jennifer E. | en_US |
dc.contributor.author | Hwang, Shih-Jen | en_US |
dc.contributor.author | Ingelsson, Erik | en_US |
dc.contributor.author | James, Alan | en_US |
dc.contributor.author | Jansen, Rick | en_US |
dc.contributor.author | Jarvelin, Marjo-Riitta | en_US |
dc.contributor.author | Joehanes, Roby | en_US |
dc.contributor.author | Johansson, Åsa | en_US |
dc.contributor.author | Johnson, Andrew D. | en_US |
dc.contributor.author | Joshi, Peter K. | en_US |
dc.contributor.author | Jousilahti, Pekka | en_US |
dc.contributor.author | Jukema, J. Wouter | en_US |
dc.contributor.author | Jula, Antti | en_US |
dc.contributor.author | Kähönen, Mika | en_US |
dc.contributor.author | Kathiresan, Sekar | en_US |
dc.contributor.author | Keavney, Bernard D. | en_US |
dc.contributor.author | Khaw, Kay-Tee | en_US |
dc.contributor.author | Knekt, Paul | en_US |
dc.contributor.author | Knight, Joanne | en_US |
dc.contributor.author | Kolcic, Ivana | en_US |
dc.contributor.author | Kooner, Jaspal S. | en_US |
dc.contributor.author | Koskinen, Seppo | en_US |
dc.contributor.author | Kristiansson, Kati | en_US |
dc.contributor.author | Kutalik, Zoltan | en_US |
dc.contributor.author | Laan, Maris | en_US |
dc.contributor.author | Larson, Marty | en_US |
dc.contributor.author | Launer, Lenore J. | en_US |
dc.contributor.author | Lehne, Benjamin | en_US |
dc.contributor.author | Lehtimäki, Terho | en_US |
dc.contributor.author | Liewald, David C. M. | en_US |
dc.contributor.author | Lin, Li | en_US |
dc.contributor.author | Lind, Lars | en_US |
dc.contributor.author | Lindgren, Cecilia M. | en_US |
dc.contributor.author | Liu, YongMei | en_US |
dc.contributor.author | Loos, Ruth J. F. | en_US |
dc.contributor.author | Lopez, Lorna M. | en_US |
dc.contributor.author | Lu, Yingchang | en_US |
dc.contributor.author | Lyytikäinen, Leo-Pekka | en_US |
dc.contributor.author | Mahajan, Anubha | en_US |
dc.contributor.author | Mamasoula, Chrysovalanto | en_US |
dc.contributor.author | Marrugat, Jaume | en_US |
dc.contributor.author | Marten, Jonathan | en_US |
dc.contributor.author | Milaneschi, Yuri | en_US |
dc.contributor.author | Morgan, Anna | en_US |
dc.contributor.author | Morris, Andrew P. | en_US |
dc.contributor.author | Morrison, Alanna C. | en_US |
dc.contributor.author | Munson, Peter J. | en_US |
dc.contributor.author | Nalls, Mike A. | en_US |
dc.contributor.author | Nandakumar, Priyanka | en_US |
dc.contributor.author | Nelson, Christopher P. | en_US |
dc.contributor.author | Niiranen, Teemu | en_US |
dc.contributor.author | Nolte, Ilja M. | en_US |
dc.contributor.author | Nutile, Teresa | en_US |
dc.contributor.author | Oldehinkel, Albertine J. | en_US |
dc.contributor.author | Oostra, Ben A. | en_US |
dc.contributor.author | O'Reilly, Paul F. | en_US |
dc.contributor.author | Org, Elin | en_US |
dc.contributor.author | Padmanabhan, Sandosh | en_US |
dc.contributor.author | Palmas, Walter | en_US |
dc.contributor.author | Palotie, Aarno | en_US |
dc.contributor.author | Pattie, Alison | en_US |
dc.contributor.author | Penninx, Brenda W. J. H. | en_US |
dc.contributor.author | Perola, Markus | en_US |
dc.contributor.author | Peters, Annette | en_US |
dc.contributor.author | Polasek, Ozren | en_US |
dc.contributor.author | Pramstaller, Peter P. | en_US |
dc.contributor.author | Nguyen, Quang Tri | en_US |
dc.contributor.author | Raitakari, Olli T. | en_US |
dc.contributor.author | Ren, Meixia | en_US |
dc.contributor.author | Rettig, Rainer | en_US |
dc.contributor.author | Rice, Kenneth | en_US |
dc.contributor.author | Ridker, Paul M. | en_US |
dc.contributor.author | Ried, Janina S. | en_US |
dc.contributor.author | Riese, Harriëtte | en_US |
dc.contributor.author | Ripatti, Samuli | en_US |
dc.contributor.author | Robino, Antonietta | en_US |
dc.contributor.author | Rose, Lynda M. | en_US |
dc.contributor.author | Rotter, Jerome I. | en_US |
dc.contributor.author | Rudan, Igor | en_US |
dc.contributor.author | Ruggiero, Daniela | en_US |
dc.contributor.author | Saba, Yasaman | en_US |
dc.contributor.author | Sala, Cinzia F. | en_US |
dc.contributor.author | Salomaa, Veikko | en_US |
dc.contributor.author | Samani, Nilesh J. | en_US |
dc.contributor.author | Sarin, Antti-Pekka | en_US |
dc.contributor.author | Schmidt, Reinhold | en_US |
dc.contributor.author | Schmidt, Helena | en_US |
dc.contributor.author | Shrine, Nick | en_US |
dc.contributor.author | Siscovick, David | en_US |
dc.contributor.author | Smith, Albert V. | en_US |
dc.contributor.author | Snieder, Harold | en_US |
dc.contributor.author | Sõber, Siim | en_US |
dc.contributor.author | Sorice, Rossella | en_US |
dc.contributor.author | Starr, John M. | en_US |
dc.contributor.author | Stott, David J. | en_US |
dc.contributor.author | Strachan, David P. | en_US |
dc.contributor.author | Strawbridge, Rona J. | en_US |
dc.contributor.author | Sundström, Johan | en_US |
dc.contributor.author | Swertz, Morris A. | en_US |
dc.contributor.author | Taylor, Kent D. | en_US |
dc.contributor.author | Teumer, Alexander | en_US |
dc.contributor.author | Tobin, Martin D. | en_US |
dc.contributor.author | Tomaszewski, Maciej | en_US |
dc.contributor.author | Toniolo, Daniela | en_US |
dc.contributor.author | Traglia, Michela | en_US |
dc.contributor.author | Trompet, Stella | en_US |
dc.contributor.author | Tuomilehto, Jaakko | en_US |
dc.contributor.author | Tzourio, Christophe | en_US |
dc.contributor.author | Uitterlinden, André G. | en_US |
dc.contributor.author | Vaez, Ahmad | en_US |
dc.contributor.author | van der Most, Peter J. | en_US |
dc.contributor.author | van Duijn, Cornelia M. | en_US |
dc.contributor.author | Vergnaud, Anne-Claire | en_US |
dc.contributor.author | Verwoert, Germaine C. | en_US |
dc.contributor.author | Vitart, Veronique | en_US |
dc.contributor.author | Völker, Uwe | en_US |
dc.contributor.author | Vollenweider, Peter | en_US |
dc.contributor.author | Vuckovic, Dragana | en_US |
dc.contributor.author | Watkins, Hugh | en_US |
dc.contributor.author | Wild, Sarah H. | en_US |
dc.contributor.author | Willemsen, Gonneke | en_US |
dc.contributor.author | Wilson, James F. | en_US |
dc.contributor.author | Wright, Alan F. | en_US |
dc.contributor.author | Yao, Jie | en_US |
dc.contributor.author | Zemunik, Tatijana | en_US |
dc.contributor.author | Zhang, Weihua | en_US |
dc.contributor.author | Attia, John R. | en_US |
dc.contributor.author | Butterworth, Adam S. | en_US |
dc.contributor.author | Chasman, Daniel I. | en_US |
dc.contributor.author | Conen, David | en_US |
dc.contributor.author | Cucca, Francesco | en_US |
dc.contributor.author | Danesh, John | en_US |
dc.contributor.author | Hayward, Caroline | en_US |
dc.contributor.author | Howson, Joanna M. M. | en_US |
dc.contributor.author | Laakso, Markku | en_US |
dc.contributor.author | Lakatta, Edward G. | en_US |
dc.contributor.author | Langenberg, Claudia | en_US |
dc.contributor.author | Melander, Olle | en_US |
dc.contributor.author | Mook-Kanamori, Dennis O. | en_US |
dc.contributor.author | Palmer, Colin N. A. | en_US |
dc.contributor.author | Risch, Lorenz | en_US |
dc.contributor.author | Scott, Robert A. | en_US |
dc.contributor.author | Scott, Rodney J. | en_US |
dc.contributor.author | Sever, Peter | en_US |
dc.contributor.author | Spector, Tim D. | en_US |
dc.contributor.author | van der Harst, Pim | en_US |
dc.contributor.author | Wareham, Nicholas J. | en_US |
dc.contributor.author | Zeggini, Eleftheria | en_US |
dc.contributor.author | Levy, Daniel | en_US |
dc.contributor.author | Munroe, Patricia B. | en_US |
dc.contributor.author | Newton-Cheh, Christopher | en_US |
dc.contributor.author | Brown, Morris J. | en_US |
dc.contributor.author | Metspalu, Andres | en_US |
dc.contributor.author | Hung, Adriana M. | en_US |
dc.contributor.author | O'Donnell, Christopher J. | en_US |
dc.contributor.author | Edwards, Todd L. | en_US |
dc.contributor.author | Psaty, Bruce M. | en_US |
dc.contributor.author | Tzoulaki, Ioanna | en_US |
dc.contributor.author | Barnes, Michael R. | en_US |
dc.contributor.author | Wain, Louise V. | en_US |
dc.contributor.author | Elliott, Paul | en_US |
dc.contributor.author | Caulfield, Mark J. | en_US |
dc.date.accessioned | 2020-05-13T05:04:33Z | - |
dc.date.available | 2020-05-13T05:04:33Z | - |
dc.date.issued | 2018 | - |
dc.identifier.citation | Evangelou, E., Warren, H. R., Mosen-Ansorena, D., Mifsud, B., Pazoki, R., Gao, H., . . . Caulfield, M. J. (2018). Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. Nature Genetics, 50(10), 1412-1425. doi:10.1038/s41588-018-0205-x | en_US |
dc.identifier.issn | 1061-4036 | en_US |
dc.identifier.uri | https://hdl.handle.net/10356/138835 | - |
dc.description.abstract | High blood pressure is a highly heritable and modifiable risk factor for cardiovascular disease. We report the largest genetic association study of blood pressure traits (systolic, diastolic and pulse pressure) to date in over 1 million people of European ancestry. We identify 535 novel blood pressure loci that not only offer new biological insights into blood pressure regulation but also highlight shared genetic architecture between blood pressure and lifestyle exposures. Our findings identify new biological pathways for blood pressure regulation with potential for improved cardiovascular disease prevention in the future. | en_US |
dc.description.sponsorship | NMRC (Natl Medical Research Council, S’pore) | en_US |
dc.description.sponsorship | MOH (Min. of Health, S’pore) | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | Nature Genetics | en_US |
dc.rights | © 2018 The Author(s) (Nature Publishing Group). All rights reserved. | en_US |
dc.subject | Science::Medicine | en_US |
dc.title | Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits | en_US |
dc.type | Journal Article | en |
dc.contributor.school | Lee Kong Chian School of Medicine (LKCMedicine) | en_US |
dc.identifier.doi | 10.1038/s41588-018-0205-x | - |
dc.identifier.pmid | 30224653 | - |
dc.identifier.scopus | 2-s2.0-85053701561 | - |
dc.identifier.issue | 10 | en_US |
dc.identifier.volume | 50 | en_US |
dc.identifier.spage | 1412 | en_US |
dc.identifier.epage | 1425 | en_US |
dc.subject.keywords | Cardiovascular Diseases | en_US |
dc.subject.keywords | Genome Informatics | en_US |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
Appears in Collections: | LKCMedicine Journal Articles |
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