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Title: Controllable particle hopping in optofluidic lattice for antibody screening and binding efficiency measurement
Authors: Shi, Yuzhi
Xiong, Sha
Zhang, Yantong
Chin, Lip Ket
Wu, J. H.
Chen, T. N.
Liu, Ai Qun
Keywords: Engineering::Electrical and electronic engineering::Optics, optoelectronics, photonics
Issue Date: 2018
Source: Shi, Y. Z., Xiong, S., Zhang, Y., Chin, L. K., Wu, J. H., Chen, T. N., & Liu, A. Q. (2018). Controllable particle hopping in optofluidic lattice for antibody screening and binding efficiency measurement. Proceedings of SPIE - Optical Trapping and Optical Micromanipulation XV 2018, 10723, 107231Y-. doi:10.1117/12.2319693
Abstract: Particle patterning and hopping has attracted much attention owing to their extensive involvement in many physical and biological studies. Here, by configuring an intriguing Optofluidic, we are able to pattern 500 nm particles into a 2D array in the flow stream. We also achieve a 2D patterning of cryptosporidium in the microchannel. By investing particle-particle interactions, we studies the long ignored new particle hopping mechanisms, and used them to screen antibodies. Our observed particle hopping in the flow stream completes the family of particle kinetics in optofluidic potential wells and inspires new minds in the develop new light fields in the microchannel. The 2D patterning of particles facilites the parallel culture and study of multiple biological samples in the flow stream.
ISBN: 9781510620179
DOI: 10.1117/12.2319693
Rights: Copyright 2018 Society of Photo-Optical Instrumentation Engineers (SPIE). One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:EEE Conference Papers

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