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Title: Highly sensitive, label-free detection of 2,4-dichlorophenoxyacetic acid using an optofluidic chip
Authors: Feng, Xueling
Zhang, Gong
Chin, Lip Ket
Liu, Ai Qun
Liedberg, Bo
Keywords: Engineering::Electrical and electronic engineering
Issue Date: 2017
Source: Feng, X., Zhang, G., Chin, L. K., Liu, A. Q., & Liedberg, B. (2017). Highly sensitive, label-free detection of 2,4-dichlorophenoxyacetic acid using an optofluidic chip. ACS Sensors, 2(7), 955-960. doi:10.1021/acssensors.7b00217
Project: NRF-CRP13-2014-01
Journal: ACS Sensors
Abstract: A highly sensitive approach for rapid and label-free detection of the herbicide 2,4-dichlorophenoxyacetic acid (2,4-D) using an optofluidic chip is demonstrated. The optofluidic chip is prepared by covalent immobilization of 2,4-D-bovine serum albumin (2,4-D-BSA) conjugate to an integrated microring resonator. Subsequent detection of 2,4-D carried out in a competitive immunoreaction format enables selective detection of 2,4-D in different types of water samples, including bottled, tap, and lake water, at a limit of detection (LOD) of 4.5 pg/mL and in a quantitative range of 15-105 pg/mL. The microring resonator-based optofluidic chip is reusable with ultrahigh sensitivity that offers real-time and on-site detection of low-molecular-weight targets for potential applications in food safety and environmental monitoring.
ISSN: 2379-3694
DOI: 10.1021/acssensors.7b00217
Schools: School of Electrical and Electronic Engineering 
School of Materials Science & Engineering 
Organisations: Centre for Biomimetic Sensor Science
Rights: This document is the Accepted Manuscript version of a Published Work that appeared in final form in ACS Sensors, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:EEE Journal Articles

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