Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/139104
Title: High-resolution and multi-range particle separation by microscopic vibration in an optofluidic chip
Authors: Shi, Yu Zhi
Xiong, Sha
Chin, Lip Ket
Yang, Yi
Zhang, Jing Bo
Ser, Wee
Wu, Jiu Hui
Chen, Tian Ning
Yang, Zhen Chuan
Hao, Yi Long
Liedberg, Bo
Yap, Peng Huat
Zhang, Yi
Liu, Ai Qun
Keywords: Engineering::Electrical and electronic engineering
Issue Date: 2017
Source: Shi, Y. Z., Xiong, S., Chin, L. K., Yang, Y., Zhang, J. B., Ser, W., . . . Liu, A. Q. (2017). High-resolution and multi-range particle separation by microscopic vibration in an optofluidic chip. Lab on a Chip, 17(14), 2443-2450. doi:10.1039/c7lc00484b
Journal: Lab on a Chip
Abstract: An optofluidic chip is demonstrated in experiments for high-resolution and multi-range particle separation through the optically-induced microscopic vibration effect, where nanoparticles are trapped in loosely overdamped optical potential wells created with combined optical and fluidic constraints. It is the first demonstration of separating single nanoparticles with diameters ranging from 60 to 100 nm with a resolution of 10 nm. Nanoparticles vibrate with an amplitude of 3-7 μm in the loosely overdamped potential wells in the microchannel. The proposed optofluidic device is capable of high-resolution particle separation at both nanoscale and microscale without reconfiguring the device. The separation of bacteria from other larger cells is accomplished using the same chip and operation conditions. The unique trapping mechanism and the superb performance in high-resolution and multi-range particle separation of the proposed optofluidic chip promise great potential for a diverse range of biomedical applications.
URI: https://hdl.handle.net/10356/139104
ISSN: 1473-0197
DOI: 10.1039/c7lc00484b
Rights: © 2017 The Author(s) (Royal Society of Chemistry). All rights reserved. This paper was published in Lab on a Chip and is made available with permission of The Author(s) (Royal Society of Chemistry).
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:EEE Journal Articles

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