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https://hdl.handle.net/10356/139335
Title: | Palladium-catalyzed one-pot highly regioselective 6-endo cyclization and alkylation of enynoates : synthesis of 2-alkanone pyrones | Authors: | Tanveer Ahmad Qiu, Sheng-Qi Xu, Yun-He Loh, Teck-Peng |
Keywords: | Science::Chemistry | Issue Date: | 2018 | Source: | Tanveer Ahmad, Qiu, S.-Q., Xu, Y.-H., & Loh, T.-P. (2018). Palladium-catalyzed one-pot highly regioselective 6-endo cyclization and alkylation of enynoates : synthesis of 2-alkanone pyrones. The Journal of Organic Chemistry, 83(21), 13414-13426. doi:10.1021/acs.joc.8b02198 | Journal: | The Journal of Organic Chemistry | Abstract: | The Pd(II)-catalyzed one-pot tandem cyclization/alkylation reactions of enynoates with allylic alcohols have been demonstrated. In this reaction, an innovative protocol proceeded well through Pd-catalyzed intramolecular selective 6- endo cyclization, insertion of allylic alcohols into the Pd-C bond of vinylpalladium species generated in situ, and β-hydrogen elimination processes. This conversion provides a convenient and efficient methodology for the synthesis of 2-alkanone pyrones in moderate to good yields. | URI: | https://hdl.handle.net/10356/139335 | ISSN: | 0022-3263 | DOI: | 10.1021/acs.joc.8b02198 | Schools: | School of Physical and Mathematical Sciences | Rights: | © 2018 American Chemical Society. All rights reserved. | Fulltext Permission: | none | Fulltext Availability: | No Fulltext |
Appears in Collections: | SPMS Journal Articles |
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