Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/139730
Title: Comparison of anterior segment optical coherence tomography angiography systems for corneal vascularisation
Authors: Ang, Marcus
Devarajan, Kavya
Das, Suchandrima
Stanzel, Tisha
Tan, Anna
Girard, Michael
Schmetterer, Leopold
Mehta, Jodhbir Singh
Keywords: Engineering::Materials
Issue Date: 2018
Source: Ang, M., Devarajan, K., Das, S., Stanzel, T., Tan, A., Girard, M., . . ., Mehta, J. S. (2018). Comparison of anterior segment optical coherence tomography angiography systems for corneal vascularisation. British journal of ophthalmology, 102(7), 873-877. doi:10.1136/bjophthalmol-2017-311072
Journal: British journal of ophthalmology
Abstract: Aim: To newly describe a spectral-domain (SD) optical coherence tomography angiography (OCTA) for the cornea and directly compare two OCTA system scans of the same eyes with corneal vascularisation. Methods: Cross-sectional, observational, comparative case series. We performed sequential OCTA scans (10 eyes of 10 subjects with corneal vascularisation,4 scans each eye) repeated using split-spectrum amplitude decorrelation algorithm angiography system (SSADA, AngioVue; Optovue Inc, USA) and SD OCTA (Angioscan; Nidek Co. Ltd, Japan) in the same region of interest. We analysed all scan images for repeatability, image quality and vessel density measurements and compared OCTA systems. Results: We obtained substantial interobserver repeatability in terms of image quality score (κ=0.86) for all 80 OCTA scans (median age 49 years, 50% women). The correlation was moderately good (r=0.721) when comparing vessel density measurements between OCTA systems, but greater in the SSADA compared with SD OCTA system (mean vessel density 20.3±4.9% vs 15.1±4.2%, respectively; p<0.001). Conclusion: In this pilot clinical study, we describe successful delineation of corneal vessels with substantial image quality using a new SD OCTA system. The vessel density measurements were greater using the SSADA compared with SD OCTA system in the same area of corneal vascularisation. Further studies are required to confirm the advantages, limitations and differences between these OCTA systems for the anterior segment.
URI: https://hdl.handle.net/10356/139730
ISSN: 0007-1161
DOI: 10.1136/bjophthalmol-2017-311072
Rights: © 2018 The Author(s) (BMJ Publishing Group). All rights reserved.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:MSE Journal Articles

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