Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/139730
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dc.contributor.authorAng, Marcusen_US
dc.contributor.authorDevarajan, Kavyaen_US
dc.contributor.authorDas, Suchandrimaen_US
dc.contributor.authorStanzel, Tishaen_US
dc.contributor.authorTan, Annaen_US
dc.contributor.authorGirard, Michaelen_US
dc.contributor.authorSchmetterer, Leopolden_US
dc.contributor.authorMehta, Jodhbir Singhen_US
dc.date.accessioned2020-05-21T05:34:31Z-
dc.date.available2020-05-21T05:34:31Z-
dc.date.issued2018-
dc.identifier.citationAng, M., Devarajan, K., Das, S., Stanzel, T., Tan, A., Girard, M., . . ., Mehta, J. S. (2018). Comparison of anterior segment optical coherence tomography angiography systems for corneal vascularisation. British journal of ophthalmology, 102(7), 873-877. doi:10.1136/bjophthalmol-2017-311072en_US
dc.identifier.issn0007-1161en_US
dc.identifier.urihttps://hdl.handle.net/10356/139730-
dc.description.abstractAim: To newly describe a spectral-domain (SD) optical coherence tomography angiography (OCTA) for the cornea and directly compare two OCTA system scans of the same eyes with corneal vascularisation. Methods: Cross-sectional, observational, comparative case series. We performed sequential OCTA scans (10 eyes of 10 subjects with corneal vascularisation,4 scans each eye) repeated using split-spectrum amplitude decorrelation algorithm angiography system (SSADA, AngioVue; Optovue Inc, USA) and SD OCTA (Angioscan; Nidek Co. Ltd, Japan) in the same region of interest. We analysed all scan images for repeatability, image quality and vessel density measurements and compared OCTA systems. Results: We obtained substantial interobserver repeatability in terms of image quality score (κ=0.86) for all 80 OCTA scans (median age 49 years, 50% women). The correlation was moderately good (r=0.721) when comparing vessel density measurements between OCTA systems, but greater in the SSADA compared with SD OCTA system (mean vessel density 20.3±4.9% vs 15.1±4.2%, respectively; p<0.001). Conclusion: In this pilot clinical study, we describe successful delineation of corneal vessels with substantial image quality using a new SD OCTA system. The vessel density measurements were greater using the SSADA compared with SD OCTA system in the same area of corneal vascularisation. Further studies are required to confirm the advantages, limitations and differences between these OCTA systems for the anterior segment.en_US
dc.language.isoenen_US
dc.relation.ispartofBritish journal of ophthalmologyen_US
dc.rights© 2018 The Author(s) (BMJ Publishing Group). All rights reserved.en_US
dc.subjectEngineering::Materialsen_US
dc.titleComparison of anterior segment optical coherence tomography angiography systems for corneal vascularisationen_US
dc.typeJournal Articleen
dc.contributor.schoolSchool of Materials Science & Engineeringen_US
dc.identifier.doi10.1136/bjophthalmol-2017-311072-
dc.identifier.pmid28939690-
dc.identifier.scopus2-s2.0-85041345332-
dc.identifier.issue7en_US
dc.identifier.volume102en_US
dc.identifier.spage873en_US
dc.identifier.epage877en_US
dc.subject.keywordsDiagnostic Tests/investigationen_US
dc.subject.keywordsCorneaen_US
item.fulltextNo Fulltext-
item.grantfulltextnone-
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