Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/140002
Title: Single molecule manipulation of nucleic acid structures using optical tweezers
Authors: Tan, Kwan Ann
Keywords: Science::Biological sciences::Biophysics
Science::Physics
Issue Date: 2020
Publisher: Nanyang Technological University
Abstract: Optical tweezers are versatile and precise tools that are well suited for single molecule studies. Here, optical tweezers is used to study the mechanical unfolding of five RNA structures. The studying of mechanical unfolding is crucial to understand the many cellular processes that involves RNA, like translation. We find that hairpin-like structures can unfold reversibly at pH 7.3.
URI: https://hdl.handle.net/10356/140002
Fulltext Permission: restricted
Fulltext Availability: With Fulltext
Appears in Collections:SPMS Student Reports (FYP/IA/PA/PI)

Files in This Item:
File Description SizeFormat 
Single_molecule_manipulation_of_nucleic_acid_structures_using_optical_tweezers.pdf
  Restricted Access
5.7 MBAdobe PDFView/Open

Google ScholarTM

Check

Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.