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|Title:||Single molecule manipulation of nucleic acid structures using optical tweezers||Authors:||Tan, Kwan Ann||Keywords:||Science::Biological sciences::Biophysics
|Issue Date:||2020||Publisher:||Nanyang Technological University||Abstract:||Optical tweezers are versatile and precise tools that are well suited for single molecule studies. Here, optical tweezers is used to study the mechanical unfolding of five RNA structures. The studying of mechanical unfolding is crucial to understand the many cellular processes that involves RNA, like translation. We find that hairpin-like structures can unfold reversibly at pH 7.3.||URI:||https://hdl.handle.net/10356/140002||Fulltext Permission:||restricted||Fulltext Availability:||With Fulltext|
|Appears in Collections:||SPMS Student Reports (FYP/IA/PA/PI)|
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