Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/140698
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dc.contributor.authorZheng, Jingen_US
dc.contributor.authorZhu, Mengxiangen_US
dc.contributor.authorFerracci, Gaiaen_US
dc.contributor.authorCho, Nam-Joonen_US
dc.contributor.authorLee, Bae Hoonen_US
dc.date.accessioned2020-06-01T07:51:17Z-
dc.date.available2020-06-01T07:51:17Z-
dc.date.issued2018-
dc.identifier.citationZheng, J., Zhu, M., Ferracci, G., Cho, N.-J., & Lee, B. H. (2018). Hydrolytic stability of methacrylamide and methacrylate in gelatin methacryloyl and decoupling of gelatin methacrylamide from gelatin methacryloyl through hydrolysis. Macromolecular Chemistry and Physics, 219(18), 1800266-. doi:10.1002/macp.201800266en_US
dc.identifier.issn1022-1352en_US
dc.identifier.urihttps://hdl.handle.net/10356/140698-
dc.description.abstractGelatin methacryloyl (GelMA; GM) is a promising nature-derived photocurable material that can mimic the extracellular matrix because GelMA features tailorable mechanical properties, proteolytic degradation, and good cell adhesion. GelMA contains not only methacrylamide but also methacrylate. However, the hydrolytic stability of methacrylamide and methacrylate groups of GelMA in aqueous solutions has not been scrutinized. Here, the structural change of GelMA through hydrolysis is investigated for the first time. The structural change of hydrolyzed GelMA is quantitatively identified using colorimetric and 1H NMR methods. The methacrylate groups decompose markedly at high pH solutions, but the methacrylamide groups remain stable. Further, pure gelatin methacrylamide is successfully decoupled from GelMA for a better understanding of GelMA structure and future use for biomedical applications.en_US
dc.description.sponsorshipNRF (Natl Research Foundation, S’pore)en_US
dc.language.isoenen_US
dc.relation.ispartofMacromolecular Chemistry and Physicsen_US
dc.rightsThis is the accepted version of the following article: Zheng, J., Zhu, M., Ferracci, G., Cho, N.-J., & Lee, B. H. (2018). Hydrolytic stability of methacrylamide and methacrylate in gelatin methacryloyl and decoupling of gelatin methacrylamide from gelatin methacryloyl through hydrolysis. Macromolecular Chemistry and Physics, 219(18), 1800266-, which has been published in final form at dx.doi.org/10.1002/macp.201800266. This article may be used for non-commercial purposes in accordance with the Wiley Self-Archiving Policy [https://authorservices.wiley.com/authorresources/Journal-Authors/licensing/self-archiving.html].en_US
dc.subjectEngineering::Materialsen_US
dc.titleHydrolytic stability of methacrylamide and methacrylate in gelatin methacryloyl and decoupling of gelatin methacrylamide from gelatin methacryloyl through hydrolysisen_US
dc.typeJournal Articleen
dc.contributor.schoolSchool of Materials Science & Engineeringen_US
dc.identifier.doi10.1002/macp.201800266-
dc.identifier.scopus2-s2.0-85052640598-
dc.identifier.issue18en_US
dc.identifier.volume219en_US
dc.subject.keywordsGelatin Methacrylamideen_US
dc.subject.keywordsGelatin Methacrylateen_US
item.grantfulltextnone-
item.fulltextNo Fulltext-
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