Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/141007
Title: Does oxidative stress contribute to adverse outcomes in HIV-associated TB?
Authors: Yew, Wing-Wai
Chan, Denise Puichung
Singhal, Amit
Zhang, Ying
Lee, Shui-Shan
Keywords: Science::Medicine
Issue Date: 2018
Source: Yew, W.-W., Chan, D. P., Singhal, A., Zhang, Y., & Lee, S.-S. (2018). Does oxidative stress contribute to adverse outcomes in HIV-associated TB? Journal of Antimicrobial Chemotherapy, 73(5), 1117-1120. doi:10.1093/jac/dkx509
Journal: Journal of Antimicrobial Chemotherapy
Abstract: In HIV infection, oxidative stress is a pronounced phenomenon, with likely links to HIV-related pathologies and the progression of HIV infection per se. TB is an AIDS-defining condition. HIV-associated oxidative stress, like that associated with diabetes mellitus, might adversely impact the outcomes of TB, probably through increased propensity for generation of metabolically dormant mycobacterial persisters, alongside other mechanisms. This hypothesis might help in guiding the exploration of relevant research directions to improve the care of patients.
URI: https://hdl.handle.net/10356/141007
ISSN: 0305-7453
DOI: 10.1093/jac/dkx509
Rights: © 2018 The Author(s) (published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy). All rights reserved.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:LKCMedicine Journal Articles

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