Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/142417
Title: The burden and clinical manifestation of hospitalized influenza among different pediatric age-groups in the tropics
Authors: Chong, Chia Yin
Yung, Chee Fu
Gan, Cherie
Thio, Szu-Tien
Tan, Natalie Woon Hui
Tee, Nancy Wen-Sim
Lin, Cui
Lin, Raymond Tze-Pin
Thoon, Koh Cheng
Keywords: Science::Medicine
Issue Date: 2019
Source: Chong, C. Y., Yung, C. F., Gan, C., Thio, S.-T., Tan, N. W. H., Tee, N. W.-S., . . . Thoon, K. C. (2020). The burden and clinical manifestation of hospitalized influenza among different pediatric age‐groups in the tropics. Influenza and Other Respiratory Viruses, 14(1), 46-54. doi:10.1111/irv.12692
Journal: Influenza and Other Respiratory Viruses
Abstract: Introduction: In tropical Singapore, influenza occurs all year‐round. This study of influenza‐confirmed hospitalized pediatric patients compared clinical characteristics and complications by age‐group and differences between influenza A and B. Methods: This was a retrospective study of pediatric inpatients from January 2013 to December 2014. Patients were grouped into: <6 months, 6 months to <5 years, 5‐ to <10‐year and ≥10 years. Complications were classified into neurologic, pulmonary, and other. We also calculated the incidence of hospitalized influenza cases per 100 000 age‐related population. Results: There were a total of 1272 patients with a median age of 37 months. The highest hospitalization rates were in the <6 months age‐group. Majority (75.2%) had no comorbidity; 25.6% had complications: neurologic 11.9%, pulmonary 9.6%, other 4.1%. Patients with other complications were older, male, and had the highest influenza B rates and the longest length of stay. Influenza A comprised 76.9% of cases and had higher complication rates especially neurologic, compared to influenza B. Influenza B patients were older and were more likely to develop other complications. The 6‐month to <5‐year‐age‐group had the highest complication rate (30.6%), especially neurologic. However, ≥10 years old had the highest other complications, ICU/ high‐dependency admissions and influenza B Victoria rates. Conclusions: Infants <6 months had the highest hospitalization rates for influenza. The 6‐month to <5‐year‐age‐group had the highest complication rate especially neurologic. Influenza A patients were younger, had higher seizure rates and complications compared to influenza B.
URI: https://hdl.handle.net/10356/142417
ISSN: 1750-2640
DOI: 10.1111/irv.12692
Rights: © 2019 The Authors (published by John Wiley & Sons Ltd). This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:LKCMedicine Journal Articles

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