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Title: Adipsic Diabetes Insipidus - the challenging combination of polyuria and adipsia : a case report and review of literature
Authors: Dalan, Rinkoo
Chin, Hanxin
Hoe, Jeremy
Chen, Abel
Tan, Huiling
Boehm, Bernhard Otto
Chua, Karen SuiGeok
Keywords: Science::Medicine
Issue Date: 2019
Source: Dalan, R., Chin, H., Hoe, J., Chen, A., Tan, H., Boehm, B. O., & Chua, K. S. (2019). Adipsic Diabetes Insipidus - the challenging combination of polyuria and adipsia : a case report and review of literature. Frontiers in Endocrinology, 10, 630-. doi:10.3389/fendo.2019.00630
Journal: Frontiers in Endocrinology
Abstract: Adipsic Diabetes Insipidus is a rare hypothalamic disorder characterized by a loss of thirst in response to hypernatraemia accompanied by diabetes insipidus. These occur secondary to a congregation of defects in the homeostatic mechanisms of water balance. A 27-year old Chinese female presented with Adipsic Diabetes Insipidus after cerebral arteriovenous malformation (AVM) surgery. Initial diagnosis and management was extremely challenging. Long term management required a careful interplay between low dose vasopressin analog treatment and fluids. Detailed charts of medication and sodium balance are described in the case presentation. We performed a literature search of similarly reported cases and describe the possible pathogenesis, etiology, clinical presentation, acute and chronic management, and prognosis.
ISSN: 1664-2392
DOI: 10.3389/fendo.2019.00630
Rights: © 2019 Dalan, Chin, Hoe, Chen, Tan, Boehm and Chua. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Fulltext Permission: open
Fulltext Availability: With Fulltext
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