Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributor.authorHuong, Bui Thi Maien_US
dc.contributor.authorTuyen, Le Danhen_US
dc.contributor.authorMadsen, Henryen_US
dc.contributor.authorBrimer, Leonen_US
dc.contributor.authorFriis, Henriken_US
dc.contributor.authorDalsgaard, Andersen_US
dc.identifier.citationHuong, B. T. M., Tuyen, L. D., Madsen, H., Brimer, L., Friis, H., & Dalsgaard, A. (2019). Total dietary intake and health risks associated with exposure to aflatoxin B1, cchratoxin A and fuminisins of children in Lao Cai province, Vietnam. Toxins, 11(11), 638-. doi:10.3390/toxins11110638en_US
dc.description.abstractThe health burden of foodborne mycotoxins is considerable, but particularly for children due to their lower detoxification capacity, rapid growth and high intake of food in proportion to their weight. Through a Total Dietary Study approach, the objective was to estimate the dietary exposure and health risk caused by mycotoxins for children under 5 years living in the Lao Cai province in northern Vietnam. A total of 40 composite food samples representing 1008 individual food samples were processed and analyzed by ELISA for aflatoxin B1, ochratoxin A and fumonisins. Results showed that dietary exposure to aflatoxin B1, ochratoxin A and total fumonisins were 118.7 ng/kgbw/day, 52.6 ng/kg bw/day and 1250.0 ng/kg bw/day, respectively. Using a prevalence of hepatitis of 1%, the risk of liver cancer related to exposure of aflatoxin B1 was 12.1 cases/100,000 individual/year. Age-adjusted margin of exposure (MOE) of renal cancer associated with ochratoxin A was 127, while MOE of liver cancer associated with fumonisins was 542. Antropometric data show that 50.4% (60/119) of children were stunted, i.e. height/length for age z-scores (HAZ) below -2, and 3.4% (4/119) of children were classified as wasted, i.e. weight for height z-scores (WHZ) below -2. A significant negative relationship between dietary exposure to individual or mixture of mycotoxins and growth of children was observed indicating that the high mycotoxin intake contributed to stunning in the children studied.en_US
dc.rights© 2019 The Authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (
dc.subjectEngineering::Chemical engineeringen_US
dc.titleTotal dietary intake and health risks associated with exposure to aflatoxin B1, cchratoxin A and fuminisins of children in Lao Cai province, Vietnamen_US
dc.typeJournal Articleen
dc.contributor.schoolSchool of Chemical and Biomedical Engineeringen_US
dc.description.versionPublished versionen_US
dc.subject.keywordsRisk Assessmenten_US
dc.subject.keywordsTotal Diet Studyen_US
item.fulltextWith Fulltext-
Appears in Collections:SCBE Journal Articles

Citations 20

Updated on Mar 30, 2023

Web of ScienceTM
Citations 20

Updated on Mar 28, 2023

Page view(s)

Updated on Apr 1, 2023

Download(s) 50

Updated on Apr 1, 2023

Google ScholarTM




Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.