Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/143678
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dc.contributor.authorLiu, Gongyuanen_US
dc.contributor.authorZhang, Shichaoen_US
dc.contributor.authorShi, Yunhaoen_US
dc.contributor.authorHuang, Xiaoyuen_US
dc.contributor.authorTang, Yunyunen_US
dc.contributor.authorChen, Pengen_US
dc.contributor.authorSi, Weilien_US
dc.contributor.authorHuang, Weien_US
dc.contributor.authorDong, Xiaochenen_US
dc.date.accessioned2020-09-16T07:59:18Z-
dc.date.available2020-09-16T07:59:18Z-
dc.date.issued2018-
dc.identifier.citationLiu, G., Zhang, S., Shi, Y., Huang, X., Tang, Y., Chen, P., ... Dong, X. (2018). “Wax-sealed” theranostic nanoplatform for enhanced afterglow imaging-guided photothermally triggered photodynamic therapy. Advanced Functional Materials, 28(42), 1804317-. doi:10.1002/adfm.201804317en_US
dc.identifier.issn1616-3028en_US
dc.identifier.urihttps://hdl.handle.net/10356/143678-
dc.description.abstractHerein, persistent luminescence nanoparticles (PLNPs) and photosensitizer are integrated for cancer theranostics with high specificity and without the need of continuous illumination. Specifically, ZnGa1.996O4:Cr0.004 (PLNPs) and IR780 (photosensitizer) are encapsulated by a temperature‐responsive “wax‐seal” composed of oleic acid and hexadecanol. The seal prevents luminescence quenching and premature initiation of photodynamic therapy (PDT), until it is melted down by heat stimulus. After photothermal activation, the near‐infrared afterglow offered by PLNPs provides imaging with high signal‐to‐background ratio because of the absence of tissue autofluorescence, as well as continuously excited photosensitizer for reactive oxygen species generation. Such theranostic nanoplatform offers multimodal imaging–guided localized cancer PDT.en_US
dc.language.isoenen_US
dc.relation.ispartofAdvanced Functional Materialsen_US
dc.rights© 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. All rights reserved.en_US
dc.subjectEngineering::Bioengineeringen_US
dc.title“Wax-sealed” theranostic nanoplatform for enhanced afterglow imaging-guided photothermally triggered photodynamic therapyen_US
dc.typeJournal Articleen
dc.contributor.schoolSchool of Chemical and Biomedical Engineeringen_US
dc.identifier.doi10.1002/adfm.201804317-
dc.identifier.issue42en_US
dc.identifier.volume28en_US
dc.identifier.spage1804317en_US
dc.subject.keywordsAfterglow Imagingen_US
dc.subject.keywordsCancer Theranosticsen_US
item.fulltextNo Fulltext-
item.grantfulltextnone-
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