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Title: Validation of the Brief Negative Symptom Scale and its association with functioning
Authors: Ang, Mei San
Rekhi, Gurpreet
Lee, Jimmy
Keywords: Science::Medicine
Issue Date: 2019
Source: Ang, M. S., Rekhi, G., & Lee, J. (2019). Validation of the Brief Negative Symptom Scale and its association with functioning. Schizophrenia Research, 208, 97–104. doi:10.1016/j.schres.2019.04.005
Journal: Schizophrenia research 
Abstract: Introduction: The Brief Negative Symptom Scale (BNSS) includes five domains of negative symptoms suggested by the NIMH Consensus Development Conference (anhedonia, asociality, avolition, blunted affect, and alogia), which could be clustered into two factors — Motivation-Pleasure (MAP) and Emotional Expressivity (EE). Our study aims to examine the psychometric properties of BNSS, and its association with functioning. Methods: 274 individuals with schizophrenia were assessed on the BNSS, Positive and Negative Syndrome Scale (PANSS), Scale for the Assessment of Negative Symptoms (SANS), Global Assessment of Functioning Scale (GAF), Calgary Depression Scale for Schizophrenia (CDSS), and Simpson-Angus Extrapyramidal Side Effects Scale (SAS). Internal consistency was examined using Cronbach's alpha. Concurrent, discriminant, and construct validity were examined. Factor structure of BNSS was explored using confirmatory factor analyses. Association between GAF and BNSS was examined with GAF as the dependent variable and BNSS Total, MAP and EE, and BNSS five domains as independent variables in three multiple regression models after controlling for covariates. Results:BNSS showed good internal consistency (Cronbach's alpha = 0.880) and validity. The five-factor model fit the data better than the two-factor model; a second-order model was superior to both models. More severe symptoms on BNSS Total (B = −0.438, p < .001), MAP (B = −0.876, p < .001), Avolition (B = −2.503, p < .001) and Asociality (B = −0.950, p = .001) were associated with lower GAF. Conclusion: Our results lend support to the use of BNSS in clinical practice and in future research into negative symptoms. Composite scores could be computed using either the five-factor or second-order models. Negative symptoms, particularly MAP, avolition and asociality, were associated with functioning.
ISSN: 1573-2509
DOI: 10.1016/j.schres.2019.04.005
Schools: Lee Kong Chian School of Medicine (LKCMedicine) 
Rights: © 2019 Elsevier B.V. All rights reserved. This paper was published in Schizophrenia research and is made available with permission of Elsevier B.V.
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:LKCMedicine Journal Articles

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