Please use this identifier to cite or link to this item:
https://hdl.handle.net/10356/144807| Title: | Hepatic PPARα is critical in the metabolic adaptation to sepsis | Authors: | Paumelle, Réjane Haas, Joel T. Hennuyer, Nathalie Baugé, Eric Deleye, Yann Mesotten, Dieter Langouche, Lies Vanhoutte, Jonathan Cudejko, Céline Wouters, Kristiaan Hannou, Sarah Anissa Legry, Vanessa Lancel, Steve Lalloyer, Fanny Polizzi, Arnaud Smati, Sarra Gourdy, Pierre Vallez, Emmanuelle Bouchaert, Emmanuel Derudas, Bruno Dehondt, Hélène Gheeraert, Céline Fleury, Sébastien Tailleux, Anne Montagner, Alexandra Wahli, Walter Van Den Berghe, Greet Guillou, Hervé Dombrowicz, David Staels, Bart |
Keywords: | Science::Medicine | Issue Date: | 2019 | Source: | Paumelle, R., Haas, J. T., Hennuyer, N., Baugé, E., Deleye, Y., Mesotten, D., . . . Staels, B. (2019). Hepatic PPARα is critical in the metabolic adaptation to sepsis. Journal of Hepatology, 70(5), 963-973. doi:10.1016/j.jhep.2018.12.037 | Journal: | Journal of Hepatology | Abstract: | Although the role of inflammation to combat infection is known, the contribution of metabolic changes in response to sepsis is poorly understood. Sepsis induces the release of lipid mediators, many of which activate nuclear receptors such as the peroxisome proliferator-activated receptor (PPAR)α, which controls both lipid metabolism and inflammation. We aimed to elucidate the previously unknown role of hepatic PPARα in the response to sepsis. | URI: | https://hdl.handle.net/10356/144807 | ISSN: | 0168-8278 | DOI: | 10.1016/j.jhep.2018.12.037 | Rights: | © 2019 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved | Fulltext Permission: | none | Fulltext Availability: | No Fulltext |
| Appears in Collections: | LKCMedicine Journal Articles |
SCOPUSTM
Citations
10
34
Updated on Mar 24, 2023
Web of ScienceTM
Citations
10
34
Updated on Mar 30, 2023
Page view(s)
248
Updated on Mar 29, 2023
Google ScholarTM
Check
Altmetric
Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.