Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/144881
Title: Design rationale for stimuli-responsive, semi-interpenetrating polymer network hydrogels–a quantitative approach
Authors: Gupta, Nupur
Liang, Yen Nan
Lim, Jacob Song Kiat
Hu, Xiao
Keywords: Engineering::Materials
Issue Date: 2020
Source: Gupta, N., Liang, Y. N., Lim, J. S. K., & Hu, X. (2020). Design rationale for stimuli-responsive, semi-interpenetrating polymer network hydrogels–a quantitative approach. Macromolecular Rapid Communications, 41(21), 2000199-. doi:10.1002/marc.202000199
Journal: Macromolecular Rapid Communications 
Abstract: Stimuli‐responsive semi‐interpenetrating polymer network (semi‐IPN) hydrogels form an important class of polymers for their tunable properties via molecular design. They are widely investigated for a diverse range of applications including drug delivery, sensors, actuators, and osmotic agents. However, in‐depth studies on some of the critical design principles affecting diffusion/leaching of linear polymer from semi‐IPN hydrogels are lacking. Herein, for the first time, by preparing a series of model semi‐IPN hydrogels based on thermally responsive poly (N‐isopropyl acrylamide) (PNIPAM) network and linear poly(sodium acrylate) (PSA), a systematic and quantitative study concerning linear polymer chain retention and swelling/deswelling kinetics is reported. The study shows that PSA retention is significantly affected not only by PSA molecular weight and concentration, but also by polymerization temperature, which could be linked to homogeneity and internal morphology of the hydrogel. Surprisingly, there is no obvious influence of crosslinking density of PNIPAM network toward PSA retention, while faster swelling and deswelling at higher crosslinking density are observed in terms of swelling rate constant and deswelling activation energy. These findings offer new insights on the factors affecting structural and physicochemical properties of such semi‐IPN hydrogels, which should in turn serve as a general guideline for materials design.
URI: https://hdl.handle.net/10356/144881
ISSN: 1022-1336
DOI: 10.1002/marc.202000199
Rights: This is the accepted version of the following article: Gupta, N., Liang, Y. N., Lim, J. S. K., & Hu, X. (2020). Design rationale for stimuli-responsive, semi-interpenetrating polymer network hydrogels–a quantitative approach. Macromolecular Rapid Communications, 41(21), 2000199-. doi:10.1002/marc.202000199, which has been published in final form at 10.1002/marc.202000199. This article may be used for non-commercial purposes in accordance with the Wiley Self-Archiving Policy [https://authorservices.wiley.com/authorresources/Journal-Authors/licensing/self-archiving.html].
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:NEWRI Journal Articles

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