Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/144910
Full metadata record
DC FieldValueLanguage
dc.contributor.authorPal, Kumar Bhaskaren_US
dc.contributor.authorGuo, Aoxinen_US
dc.contributor.authorDas, Mrinmoyen_US
dc.contributor.authorBáti, Gáboren_US
dc.contributor.authorLiu, Xue-Weien_US
dc.date.accessioned2020-12-03T02:45:46Z-
dc.date.available2020-12-03T02:45:46Z-
dc.date.issued2020-
dc.identifier.citationPal, K. B., Guo, A., Das, M., Báti, G., & Liu, X.-W. (2020). Superbase-catalyzed stereo- and regioselective glycosylation with 2‑nitroglycals : facile access to 2‑amino-2-deoxy‑O‑glycosides. ACS Catalysis, 10(12), 6707-6715. doi:10.1021/acscatal.0c00753en_US
dc.identifier.issn2155-5435en_US
dc.identifier.urihttps://hdl.handle.net/10356/144910-
dc.description.abstractAn efficient superbase-catalyzed stereo- and regio-selective glycosylation of 2-nitroglycals with high functional group compatibility is reported. The ion pair generated from alcohol and a catalytic amount of P4-t-Bu was vital for the successful implementation of this stereoselective glycosylation under mild conditions, producing moderate to good yields. Under reported reaction conditions, 2-nitrogalactals produce α-stereoisomers exclusively, while 2-nitroglucal yielded more β-products. The notable difference between the outcomes was investigated by the density functional theory (DFT) study. In addition, we have synthesized the key intermediate of a mucin-type core-6 glycoconjugate, thus illustrating the synthetic potency of this method.en_US
dc.language.isoenen_US
dc.relationNRF2016NRF-NSFC002-005en_US
dc.relation.ispartofACS Catalysisen_US
dc.rightsThis document is the Accepted Manuscript version of a Published Work that appeared in final form in ACS Catalysis, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acscatal.0c00753en_US
dc.subjectScience::Chemistryen_US
dc.titleSuperbase-catalyzed stereo- and regioselective glycosylation with 2‑nitroglycals : facile access to 2‑amino-2-deoxy‑O‑glycosidesen_US
dc.typeJournal Articleen
dc.contributor.schoolSchool of Physical and Mathematical Sciencesen_US
dc.identifier.doi10.1021/acscatal.0c00753-
dc.description.versionAccepted versionen_US
dc.identifier.issue12en_US
dc.identifier.volume10en_US
dc.identifier.spage6707en_US
dc.identifier.epage6715en_US
dc.subject.keywords2-Nitroglycalsen_US
dc.subject.keywordsSuperbaseen_US
item.grantfulltextopen-
item.fulltextWith Fulltext-
Appears in Collections:SPMS Journal Articles

PublonsTM
Citations 20

4
Updated on Mar 5, 2021

Page view(s)

174
Updated on Aug 10, 2022

Download(s) 50

17
Updated on Aug 10, 2022

Google ScholarTM

Check

Altmetric


Plumx

Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.