Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/145308
Full metadata record
DC FieldValueLanguage
dc.contributor.authorLee, Yan Junen_US
dc.contributor.authorKoe, Amelia S.en_US
dc.contributor.authorAshokan, Archanaen_US
dc.contributor.authorMitra, Rupshien_US
dc.date.accessioned2020-12-17T01:48:52Z-
dc.date.available2020-12-17T01:48:52Z-
dc.date.issued2020-
dc.identifier.citationLee, Y. J., Koe, A. S., Ashokan, A., & Mitra, R. (2020). Female rats are resilient to the behavioral effects of maternal separation stress and exhibit stress-induced neurogenesis. Heliyon, 6(8), e04753-. doi:10.1016/j.heliyon.2020.e04753en_US
dc.identifier.issn2405-8440en_US
dc.identifier.urihttps://hdl.handle.net/10356/145308-
dc.description.abstractEarly-life stress causes anxiogenesis and sensitivity of stress endocrine axis, facilitated by changes in the basolateral amygdala and hippocampal neurogenesis. In this report, we examined if male-like relationship between early-life stress and anxiety was recapitulated in female rats, along with related neurobiological substrates of the amygdala and the hippocampus. Maternal separation, a paradigm consistently utilized in male rats in most previously published scripts, did not cause similar behavioral consequences in females. Maternal separation caused an increase in adult hippocampal neurogenesis in females without causing substantial differences in dendritic arbors of the basolateral amygdala. Thus, female rats displayed remarkable resilience in the emotional consequences of early-life stress.en_US
dc.description.sponsorshipMinistry of Education (MOE)en_US
dc.language.isoenen_US
dc.relationRG 46/12en_US
dc.relation.ispartofHeliyonen_US
dc.rights© 2020 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).en_US
dc.subjectScience::Biological sciencesen_US
dc.titleFemale rats are resilient to the behavioral effects of maternal separation stress and exhibit stress-induced neurogenesisen_US
dc.typeJournal Articleen
dc.contributor.schoolSchool of Biological Sciencesen_US
dc.identifier.doi10.1016/j.heliyon.2020.e04753-
dc.description.versionPublished versionen_US
dc.identifier.pmid32885081-
dc.identifier.issue8en_US
dc.identifier.volume6en_US
dc.subject.keywordsAmygdalaen_US
dc.subject.keywordsAnxietyen_US
dc.description.acknowledgementThis work was supported by the Ministry of Education , Singapore (# RG 46/12, to Rupshi Mitra).en_US
item.grantfulltextopen-
item.fulltextWith Fulltext-
Appears in Collections:SBS Journal Articles
Files in This Item:
File Description SizeFormat 
PIIS2405844020315966.pdf560.9 kBAdobe PDFView/Open

Page view(s)

148
Updated on Jun 29, 2022

Download(s)

14
Updated on Jun 29, 2022

Google ScholarTM

Check

Altmetric


Plumx

Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.