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Title: First-in-man feasibility study of a novel ingestible magnetically inflated balloon capsule for treatment of obesity
Authors: Kaan, Hung Leng
Phan, Phuoc Thien
Tiong, Anthony Meng Huat
Miyasaka, Muneaki
Phee, Soo Jay
Ho, Khek Yu
Keywords: Engineering::Mechanical engineering
Issue Date: 2020
Source: Kaan, H. L., Phan, P. T., Tiong, A. M. H., Miyasaka, M., Phee, S. J., & Ho, K. Y. (2020). First-in-man feasibility study of a novel ingestible magnetically inflated balloon capsule for treatment of obesity. Endoscopy International Open, 8(5), E607-E610. doi:10.1055/a-1127-2991
Journal: Endoscopy International Open
Abstract: Intragastric balloons (IGBs) are an established treatment option for obesity. Major barriers to dissemination of IGBs include lack of long-term efficacy outcomes, safety concerns, cost, and tolerability. We developed a novel ingestible magnetically inflated balloon capsule (IMI-BC) in hopes of overcoming these challenges. The IMI-BC is significantly cheaper than IGBs currently available on the market. We performed proof-of-concept animal studies and a first-in-human feasibility study to demonstrate the feasibility of inflating the IMI-BC using an external magnet. Further studies are currently being conducted to evaluate the safety, tolerability, and long-term efficacy of the IMI-BC. When fully developed, we anticipate that this device will benefit obese patients.
ISSN: 2364-3722
DOI: 10.1055/a-1127-2991
Rights: © 2020 The Author(s) (published by Georg Thieme Verlag KG Stuttgart · New York). This is an open-access article distributed under the terms of the Creative Commons Attribution License.
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:MAE Journal Articles

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