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Title: The mechanisms and the applications of antibacterial polymers in surface modification on medical devices
Authors: Qiu, Haofeng
Si, Zhangyong
Luo, Yang
Feng, Peipei
Wu, Xujin
Hou, Wenjia
Zhu, Yabin
Chan-Park, Mary B.
Xu, Long
Huang, Dongmei
Keywords: Engineering::Bioengineering
Issue Date: 2020
Source: Qiu, H., Si, Z., Luo, Y., Feng, P., Wu, X., Hou, W., . . . Huang, D. (2020). The mechanisms and the applications of antibacterial polymers in surface modification on medical devices. Frontiers in Bioengineering and Biotechnology, 8, 910-. doi:10.3389/fbioe.2020.00910
Project: MOE2018-T3-1-003 
Journal: Frontiers in Bioengineering and Biotechnology 
Abstract: Medical device contamination caused by microbial pathogens such as bacteria and fungi has posed a severe threat to the patients’ health in hospitals. Due to the increasing resistance of pathogens to antibiotics, the efficacy of traditional antibiotics treatment is gradually decreasing for the infection treatment. Therefore, it is urgent to develop new antibacterial drugs to meet clinical or civilian needs. Antibacterial polymers have attracted the interests of researchers due to their unique bactericidal mechanism and excellent antibacterial effect. This article reviews the mechanism and advantages of antimicrobial polymers and the consideration for their translation. Their applications and advances in medical device surface coating were also reviewed. The information will provide a valuable reference to design and develop antibacterial devices that are resistant to pathogenic infections.
ISSN: 2296-4185
DOI: 10.3389/fbioe.2020.00910
Schools: School of Chemical and Biomedical Engineering 
Rights: © 2020 Qiu, Si, Luo, Feng, Wu, Hou, Zhu, Chan-Park, Xu and Huang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:SCBE Journal Articles

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