Purification, characterization and expression in Eukaryotic cells of recombinant integration host factor variants : applications in basic research and biotechnology.

Abstract

Integration host factor (IHF) is a heterodimeric Escherichia coli protein that plays important roles in a variety of cellular processes including site-specific recombination, transcription, replication, and DNA compaction (reviewed in 1,2). IHF exerts its biological functions through binding at specific DNA sites characterized by a limited consensus sequence(3).