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Title: Effects of choral singing versus health education on cognitive decline and aging : a randomized controlled trial
Authors: Feng, Lei
Romero-Garcia, Rafael
Suckling, John
Tan, Jasmine
Larbi, Anis
Cheah, Irwin
Wong, Glenn
Tsakok, Maurine
Lanskey, Bernard
Lim, Darius
Li, Jialiang
Yang, Joanna
Goh, Benjamin
Teck, Tristan Gwee Chen
Ho, Allan
Wang, Xiu
Yu, Jin-Tai
Zhang, Can
Tan, Crystal
Chua, Michelle
Li, Junhua
Totman, John J.
Wong, Caroline
Loh, Marie
Foo, Roger
Tan, Chay Hoon
Goh, Lee Gan
Mahendran, Rathi
Kennedy, Brian K.
Kua, Ee-Heok
Keywords: Science::Medicine
Issue Date: 2020
Source: Feng, L., Romero-Garcia, R., Suckling, J., Tan, J., Larbi, A., Cheah, I., . . . Kua, E.-H. (2020). Effects of choral singing versus health education on cognitive decline and aging : a randomized controlled trial. Aging, 12(24), 24798-24816. doi:10.18632/aging.202374
Project: MOH/NIC/COG06/2017
Journal: Aging
Abstract: We conducted a randomized controlled trial to examine choral singing's effect on cognitive decline in aging. Older Singaporeans who were at high risk of future dementia were recruited: 47 were assigned to choral singing intervention (CSI) and 46 were assigned to health education program (HEP). Participants attended weekly one-hour choral singing or weekly one-hour health education for two years. Change in cognitive function was measured by a composite cognitive test score (CCTS) derived from raw scores of neuropsychological tests; biomarkers included brain magnetic resonance imaging, oxidative damage and immunosenescence. The average age of the participants were 70 years and 73/93 (78.5%) were female. The change of CCTS from baseline to 24 months was 0.05 among participants in the CSI group and -0.1 among participants in the HEP group. The between-group difference (0.15, p=0.042) became smaller (0.12, p=0.09) after adjusting for baseline CCTS. No between-group differences on biomarkers were observed. Our data support the role of choral singing in improving cognitive health in aging. The beneficial effect is at least comparable than that of health education in preventing cognitive decline in a community of elderly people. Biological mechanisms underlying the observed efficacy should be further studied.
ISSN: 1945-4589
DOI: 10.18632/aging.202374
Rights: © 2020 Feng et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Fulltext Permission: open
Fulltext Availability: With Fulltext
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