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Title: Cohort profile : the diet and healthy aging (DaHA) study in Singapore
Authors: Yu, Rongjun
Sun, Ye
Ye, Kaisy Xinhong
Feng, Qiushi
Lim, Su Lin
Mahendran, Rathi
Cheah, Irwin Kee-Mun
Foo, Roger Sik Yin
Chua, Ru Yuan
Gwee, Xinyi
Loh, Marie
Sarmugam, Rani
Khine, Wei Wei Thwe
Chao, Yin Xia
Larbi, Anis
Lee, Yuan Kun
Kumar, Alan Prem
Kennedy, Brian K.
Kua, Ee-Heok
Feng, Lei
Keywords: Science::Medicine
Issue Date: 2020
Source: Yu, R., Sun, Y., Ye, K. X., Feng, Q., Lim, S. L., Mahendran, R., . . . Feng, L. (2020). Cohort profile : the diet and healthy aging (DaHA) study in Singapore. Aging, 12(23), 23889-23899. doi:10.18632/aging.104051
Project: NMRC/TA/0053/2016
Journal: Aging
Abstract: How diet is related with cognition and health has not been systematically examined in Asians whose eating habits are very different from their counterparts in the West and the biological mechanisms underlying such links are not well known yet. The diet and healthy aging (DaHA) study is a community-based longitudinal study conducted to examine the role of diet and nutrition in promoting cognitive, emotional, and physical health among community-living elderly Singaporeans. The first wave of DaHA, conducted from 2011 to 2017, provided detailed information on diet and baseline cognitive function and health from 1010 community-living elderly in Singapore. Biomarkers of oxidative stress, systemic inflammation, and genetic information were collected. The ongoing second wave of DaHA is conducted from 2017 to 2020, which provides follow- up assessments using established cognitive tests and clinical tools. This well-characterized cohort, with its archived biological samples and high-quality data on diet and lifestyle factors will allow researchers to explore the relationships among diet, nutrition, genes, cognition, mental and physical health in an extremely cost-effective manner. Translations of the research findings into clinical and public health practices will potentially help to promote cognitive health at the population level and reduce healthcare costs related to cognitive impairment.
ISSN: 1945-4589
DOI: 10.18632/aging.104051
Rights: © 2020 Yu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:LKCMedicine Journal Articles

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