Please use this identifier to cite or link to this item:
https://hdl.handle.net/10356/146483
Title: | Near-infrared light-sensitive liposomes for enhanced plasmid DNA transfection | Authors: | Wiraja, Christian Mathiyazhakan, Malathi Movahedi, Fatemeh Upputuri, Paul Kumar Cheng, Yingying Pramanik, Manojit Yang, Liang Becker, David Laurence Xu, Chenjie |
Keywords: | Engineering::Bioengineering | Issue Date: | 2016 | Source: | Wiraja, C., Mathiyazhakan, M., Movahedi, F., Upputuri, P. K., Cheng, Y., Pramanik, M., ... Xu, C. (2016). Near-infrared light-sensitive liposomes for enhanced plasmid DNA transfection. Bioengineering and Translational Medicine, 1(3), 357-364. doi:10.1002/btm2.10020 | Journal: | Bioengineering and Translational Medicine | Abstract: | Near-infrared (NIR) light-responsive liposomes are attractive carriers for targeted and controlled drug delivery to the superficial organ or tissue (e.g., skin). This work describes the development of NIR-responsive liposomes by incorporating gold nanostars within liposomes composed of Phospholipon 90 g and cholesterol. Following cellular delivery, photothermal effect around the gold nanostar upon NIR stimulation induces microcavitation and liposome phase transition which consequently triggers the release of encapsulated molecules. Taking GFP plasmid as an example, we demonstrate enhanced gene transfection into fibroblasts following NIR treatment. | URI: | https://hdl.handle.net/10356/146483 | ISSN: | 2380-6761 | DOI: | 10.1002/btm2.10020 | Schools: | School of Chemical and Biomedical Engineering | Rights: | © 2016 The Authors. Bioengineering & Translational Medicine is published by Wiley Periodicals, Inc. on behalf of The American Institute of Chemical Engineers. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. | Fulltext Permission: | open | Fulltext Availability: | With Fulltext |
Appears in Collections: | SCBE Journal Articles |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Near-infrared light-sensitive liposomes for enhanced plasmidDNA transfection.pdf | 1.15 MB | Adobe PDF | View/Open |
Web of ScienceTM
Citations
20
20
Updated on Oct 26, 2023
Page view(s) 50
453
Updated on Mar 18, 2024
Download(s) 50
64
Updated on Mar 18, 2024
Google ScholarTM
Check
Altmetric
Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.