Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/146552
Title: Recent advances in photoacoustic contrast agents for in vivo imaging
Authors: Upputuri, Paul Kumar
Pramanik, Manojit
Keywords: Engineering::Bioengineering
Issue Date: 2020
Source: Upputuri, P. K., & Pramanik, M. (2020). Recent advances in photoacoustic contrast agents for in vivo imaging. Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 12(4), e1618-. doi:10.1002/wnan.1618
Journal: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology
Abstract: Photoacoustic imaging (PAI) is a noninvasive hybrid imaging modality offering rich optical contrast and high depth-to-resolution ratio deep-tissue imaging. Endogenous chromophores present in the body such as hemoglobin, lipid, melanin, and so on provide strong photoacoustic contrast due to their strong light absorption in certain optical window. To enhance the performance of PAI further, researchers have developed several exogenous contrast agents such as metallic nanoparticles, carbon-based nanomaterials, quantum dots, organic small molecules, semiconducting polymer nanoparticles, and so on. These exogenous contrast agents not only help improving the imaging contrast, but also make targeted molecular imaging possible. In this review article, we first discuss the state-of-the-art PAI techniques with endogenous contrast mechanism. Later, we provide an overview of recent progress in the development of exogenous photoacoustic contrast agents for in vivo imaging applications. Finally, we present the pros/cons of the existing PA contrast agents along with future challenges of contrast agent-based PAI for biomedical applications. This article is categorized under: Diagnostic Tools > Diagnostic Nanodevices Diagnostic Tools > In Vivo Nanodiagnostics and Imaging.
URI: https://hdl.handle.net/10356/146552
ISSN: 1939-0041
DOI: 10.1002/wnan.1618
Rights: This is the peer reviewed version of the following article: Upputuri, P. K., & Pramanik, M. (2020). Recent advances in photoacoustic contrast agents for in vivo imaging. Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 12(4), e1618-. doi:10.1002/wnan.1618, which has been published in final form at https://doi.org/10.1002/wnan.1618. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
Fulltext Permission: embargo_20210831
Fulltext Availability: With Fulltext
Appears in Collections:SCBE Journal Articles

Files in This Item:
File Description SizeFormat 
WIREs_revision_final.pdf
  Until 2021-08-31
2.78 MBAdobe PDFUnder embargo until Aug 31, 2021

SCOPUSTM   
Citations 20

13
Updated on Mar 8, 2021

PublonsTM
Citations 20

10
Updated on Mar 8, 2021

Page view(s)

41
Updated on Jun 16, 2021

Google ScholarTM

Check

Altmetric


Plumx

Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.