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dc.contributor.authorSharma, Arunimaen_US
dc.contributor.authorIshak, Noreenen_US
dc.contributor.authorTeoh, Swee-Hinen_US
dc.contributor.authorCheung, Christineen_US
dc.contributor.authorPramanik, Manojiten_US
dc.identifier.citationSharma, A., Ishak, N., Teoh, S.-H., Cheung, C., & Pramanik, M. (2020). Photoacoustic imaging of live chicken embryo at multiple developmental stages. Proceedings of SPIE - Photons Plus Ultrasound: Imaging and Sensing 2020, 11240, 108-. doi:10.1117/12.2544534en_US
dc.description.abstractChicken embryo remains a commonly used model for biomedical research due to its ease of availability, accessibility for surgical manipulations, and biological similarities with humans. Although, it is being extensively used for cancer, cardiovascular, and developmental studies, non-destructive imaging of live embryo vasculature with high optical contrast remains a challenge. In this work, photoacoustic tomography of chicken embryos developing in bioengineered eggshell was performed. Chicken embryos at different developmental stages were irradiated with laser pulses at wavelengths 532 nm and 740 nm to acquire cross sectional images at various depths. We have shown a label free method for imaging of live chicken embryo while maintaining its integrity. We demonstrated that our method has the potential to be a powerful non-invasive imaging method for studying vasculature growth and development in chicken embryos.en_US
dc.description.sponsorshipAgency for Science, Technology and Research (A*STAR)en_US
dc.rightsCopyright 2020 Society of Photo-Optical Instrumentation Engineers (SPIE). One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.en_US
dc.titlePhotoacoustic imaging of live chicken embryo at multiple developmental stagesen_US
dc.typeConference Paperen
dc.contributor.schoolSchool of Chemical and Biomedical Engineeringen_US
dc.contributor.schoolLee Kong Chian School of Medicine (LKCMedicine)en_US
dc.contributor.conferenceSPIE - Photons Plus Ultrasound: Imaging and Sensing 2020en_US
dc.description.versionAccepted versionen_US
dc.subject.keywordsPhotoacoustic Imagingen_US
dc.subject.keywordsPhotoacoustic Tomographyen_US
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