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https://hdl.handle.net/10356/146770
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DC Field | Value | Language |
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dc.contributor.author | Setyawati, Magdiel Inggrid | en_US |
dc.contributor.author | Zhao, Zhitong | en_US |
dc.contributor.author | Ng, Kee Woei | en_US |
dc.date.accessioned | 2021-03-10T05:27:45Z | - |
dc.date.available | 2021-03-10T05:27:45Z | - |
dc.date.issued | 2020 | - |
dc.identifier.citation | Setyawati, M. I., Zhao, Z., & Ng, K. W. (2020). Transformation of nanomaterials and its implications in gut nanotoxicology. Small, 16(36), 2001246-. doi:10.1002/smll.202001246 | en_US |
dc.identifier.issn | 1613-6810 | en_US |
dc.identifier.uri | https://hdl.handle.net/10356/146770 | - |
dc.description.abstract | Ingestion of engineered nanomaterials (ENMs) is inevitable due to their widespread utilization in the agrifood industry. Safety evaluation has become pivotal to identify the consequences on human health of exposure to these ingested ENMs. Much of the current understanding of nanotoxicology in the gastrointestinal tract (GIT) is derived from studies utilizing pristine ENMs. In reality, agrifood ENMs interact with their microenvironment, and undergo multiple physicochemical transformations, such as aggregation/agglomeration, dissolution, speciation change, and surface characteristics alteration, across their life cycle from synthesis to consumption. This work sieves out the implications of ENM transformations on their behavior, stability, and reactivity in food and product matrices and through the GIT, in relation to measured toxicological profiles. In particular, a strong emphasis is given to understand the mechanisms through which these transformations can affect ENM induced gut nanotoxicity. | en_US |
dc.description.sponsorship | Nanyang Technological University | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | Small | en_US |
dc.rights | This is the peer reviewed version of the following article: Setyawati, M. I., Zhao, Z., & Ng, K. W. (2020). Transformation of nanomaterials and its implications in gut nanotoxicology. Small, 16(36), 2001246-. doi:10.1002/smll.202001246, which has been published in final form at https://doi.org/10.1002/smll.202001246. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. | en_US |
dc.subject | Engineering::Materials::Nanostructured materials | en_US |
dc.subject | Engineering::Nanotechnology | en_US |
dc.title | Transformation of nanomaterials and its implications in gut nanotoxicology | en_US |
dc.type | Journal Article | en |
dc.contributor.school | School of Materials Science and Engineering | en_US |
dc.contributor.research | Nanyang Environment and Water Research Institute | en_US |
dc.identifier.doi | 10.1002/smll.202001246 | - |
dc.description.version | Accepted version | en_US |
dc.identifier.issue | 36 | en_US |
dc.identifier.volume | 16 | en_US |
dc.identifier.spage | 2001246 | en_US |
dc.subject.keywords | Agrifood Products | en_US |
dc.subject.keywords | Engineered Nanomaterials | en_US |
dc.description.acknowledgement | Nanyang Technological University—Harvard School of Public Health Initiative for Sustainable Nanotechnology (NTU‐Harvard SusNano). | en_US |
item.fulltext | With Fulltext | - |
item.grantfulltext | open | - |
crisitem.author.dept | School of Materials Science & Engineering | - |
Appears in Collections: | MSE Journal Articles |
Files in This Item:
File | Description | Size | Format | |
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Transformation of nanomaterials and its implications in gut nanotoxicology.pdf | 3.33 MB | Adobe PDF | View/Open |
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