Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/146874
Title: Asymmetric stepwise reductive amination of sulfonamides, sulfamates, and a phosphinamide by nickel catalysis
Authors: Zhao, Xiaohu
Xu, Haiyan
Huang, Xiaolei
Zhou, Steve Jianrong
Keywords: Science::Chemistry
Issue Date: 2019
Source: Zhao, X., Xu, H., Huang, X. & Zhou, S. J. (2019). Asymmetric stepwise reductive amination of sulfonamides, sulfamates, and a phosphinamide by nickel catalysis. Angewandte Chemie, 58(1), 292-296. https://dx.doi.org/10.1002/anie.201809930
Project: A1783c0010
Journal: Angewandte Chemie
Abstract: Asymmetric reductive amination of poorly nucleophilic sulfonamides was realized in the presence of nickel catalysts and titanium alkoxide. A wide range of ketones, including enolizable ketones and some biaryl ones, were converted into sulfonamides in excellent enantiomeric excess. The cyclization of sulfamates and intermolecular reductive amination of a diarylphosphinamide were also successful. Formic acid was used as a safe and economic surrogate of high-pressure hydrogen gas.
URI: https://hdl.handle.net/10356/146874
ISSN: 0044-8249
DOI: 10.1002/anie.201809930
Rights: © 2019 Wiley-VCH Verlag GmbH &Co. KGaA, Weinheim. All rights reserved.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:SPMS Journal Articles

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