Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/147445
Title: Supported iridium catalyst for the green synthesis of 3,3′-bis(indolyl)methanes using methanol as the bridging methylene source
Authors: Qiang, Wenwen
Liu, Xiang
Loh, Teck-Peng
Keywords: Science::Chemistry
Issue Date: 2019
Source: Qiang, W., Liu, X. & Loh, T. (2019). Supported iridium catalyst for the green synthesis of 3,3′-bis(indolyl)methanes using methanol as the bridging methylene source. ACS Sustainable Chemistry and Engineering, 7(9), 8429-8439. https://dx.doi.org/10.1021/acssuschemeng.9b00094
Journal: ACS Sustainable Chemistry and Engineering
Abstract: The first example of a heterogeneous catalyst based on hydrotalcite-derived Mg-Al oxides supported iridium (Ir/Mg AlO) for activation of methanol in the synthesis of bis(indolyl)methanes (BIMs) is reported. In this clean and reusable iridium-based catalytic system, a variety of substituted indoles were selectively converted to their corresponding BIMs in moderate to good yields with high tolerance to reducible functional groups by using methanol as a bridging methylene (-CH -) donor. The high catalytic activity and selectivity of the reaction benefit from the delicate cooperation of redox/acid-base surface sites on this artificially designed multifunctional Ir/Mg AlO catalyst. The overall simplicity, chemoselectivity and sustainability of the catalytic system make this approach a valuable and step-economical tool to construct C-C bond directly from methanol in the synthesis of more complex molecules. x 2 x
URI: https://hdl.handle.net/10356/147445
ISSN: 2168-0485
DOI: 10.1021/acssuschemeng.9b00094
Rights: © 2019 American Chemical Society. All rights reserved.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:SPMS Journal Articles

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