Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/147446
Title: Divergent C-H oxidative radical functionalization of olefins to install tertiary alkyl motifs enabled by copper catalysis
Authors: Tian, Ming-Qing
Wang, Cong
Hu, Xu-Hong
Loh, Teck-Peng
Keywords: Science::Chemistry
Issue Date: 2019
Source: Tian, M., Wang, C., Hu, X. & Loh, T. (2019). Divergent C-H oxidative radical functionalization of olefins to install tertiary alkyl motifs enabled by copper catalysis. Organic Letters, 21(6), 1607-1611. https://dx.doi.org/10.1021/acs.orglett.9b00142
Journal: Organic Letters
Abstract: An efficient tertiary alkylation reaction of olefins with 1,3-dicarbonyl compounds was developed by virtue of copper catalyst without the use of expensive ligands or additives. In contrast to alkyl Heck-type reaction, alkyl halide is not required. Notably, by varying the nitrogen and air atmosphere, the reaction selectively produces alkylation and alkylation-oxygenation products, respectively. Initial investigations revealed that an α-carbonyl alkyl radical species might be involved in the process.
URI: https://hdl.handle.net/10356/147446
ISSN: 1523-7060
DOI: 10.1021/acs.orglett.9b00142
Rights: © 2019 American Chemical Society. All rights reserved.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:SPMS Journal Articles

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