Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/147784
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dc.contributor.authorTan, Eddy Wei Pingen_US
dc.date.accessioned2021-04-19T08:25:32Z-
dc.date.available2021-04-19T08:25:32Z-
dc.date.issued2021-
dc.identifier.citationTan, E. W. P. (2021). Polycarbonate : antimicrobial polymer delivery, monomer synthesis, rapid polymerization and functionalization. Doctoral thesis, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/147784en_US
dc.identifier.urihttps://hdl.handle.net/10356/147784-
dc.description.abstractRing-opening polymerization of cyclic carbonate monomers is the most common method used to synthesize a range of polycarbonates with unique properties for various applications. This thesis will explore three different areas related to the field of polycarbonates. The first chapter will examine the therapeutic potential of coacervates formed through the complexation of positively charged guanidinium-functionalized antimicrobial polycarbonate with diblock copolymers composed of methoxy poly(ethylene glycol) and negatively charged polycarbonate. The second chapter presents two novel and simple synthetic routes to access cyclic carbonate monomers in bulk while avoiding the use of highly toxic phosgene or chloroformate reagents and tedious protection-deprotection protocols. In the final chapter, the post-polymerization routes for polycarbonate platform were expanded through the development of two new functionalization routes using para-fluoro-thiol SNAr substitution reaction.en_US
dc.language.isoenen_US
dc.publisherNanyang Technological Universityen_US
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0).en_US
dc.subjectScience::Chemistry::Organic chemistry::Polymersen_US
dc.subjectScience::Biological sciences::Microbiology::Drug Resistanceen_US
dc.titlePolycarbonate : antimicrobial polymer delivery, monomer synthesis, rapid polymerization and functionalizationen_US
dc.typeThesis-Doctor of Philosophyen_US
dc.contributor.supervisorXing Bengangen_US
dc.contributor.schoolSchool of Physical and Mathematical Sciencesen_US
dc.description.degreeDoctor of Philosophyen_US
dc.contributor.organizationA*STAR Institute of Bioengineering and Nanotechnologyen_US
dc.contributor.organizationIBM Researchen_US
dc.contributor.researchA*STAR Institute of Bioengineering and Nanotechnologyen_US
dc.contributor.supervisor2Yang Yi Yanen_US
dc.identifier.doi10.32657/10356/147784-
dc.contributor.supervisoremailBengang@ntu.edu.sg, yyyang@ibn.a-star.edu.sgen_US
item.grantfulltextembargo_20230412-
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