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Title: Recalled parental bonding interacts with oxytocin receptor gene polymorphism in modulating anxiety and avoidance in adult relationships
Authors: Cataldo, Ilaria
Bonassi, Andrea
Lepri, Bruno
Foo, Jia Nee
Setoh, Peipei
Esposito, Gianluca
Keywords: Social sciences::Psychology
Issue Date: 2021
Source: Cataldo, I., Bonassi, A., Lepri, B., Foo, J. N., Setoh, P. & Esposito, G. (2021). Recalled parental bonding interacts with oxytocin receptor gene polymorphism in modulating anxiety and avoidance in adult relationships. Brain Sciences, 11(4), 496-.
Journal: Brain Sciences
Abstract: Early interactions with significant individuals affect social experience throughout the course of a lifetime, as a repeated and prolonged perception of different levels of care, independence, or control influences the modulation of emotional regulatory processes. As many factors play a role in shaping the expectations and features of social interaction, in this study, we considered the influence of parental bonding and genetic allelic variation of oxytocin receptor gene polymorphism (rs53576) over levels of experienced anxiety and avoidance in 313 young adults belonging to two different cultural contexts, namely Italy and Singapore. Results highlighted a major effect of maternal characteristics, care, and overprotection, with differences between the two cultural groups. Additionally, the interaction between rs53576 and maternal overprotection suggested different environmental susceptibility in the Italian sample and the Singaporean one. Implications for clinical work and future steps are described in the Conclusion.
ISSN: 2076-3425
DOI: 10.3390/brainsci11040496
DOI (Related Dataset): 10.21979/N9/7NT0EG
Rights: © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:SSS Journal Articles

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