Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/148219
Title: Enantioselective three-component coupling of heteroarenes, cycloalkenes and propargylic acetates
Authors: Teng, Shenghan
Chi, Robin Yonggui
Zhou, Steve Jianrong
Keywords: Science
Issue Date: 2021
Source: Teng, S., Chi, R. Y. & Zhou, S. J. (2021). Enantioselective three-component coupling of heteroarenes, cycloalkenes and propargylic acetates. Angewandte Chemie International Edition, 60(9), 4491-4495. https://dx.doi.org/10.1002/anie.202014781
Journal: Angewandte Chemie International Edition
Abstract: Asymmetric coupling proceeds efficiently between propargylic acetates, cycloalkenes and electron-rich heteroarenes including indoles, pyrroles, activated furans and thiophenes. 2,3-Disubstituted tetrahydrofurans and pyrrolidines are produced in trans configuration and excellent enantiomeric ratios. The reaction proceeds via Wacker-type attack of nucleophilic heteroarenes on alkenes activated by allenyl PdII species.
URI: https://hdl.handle.net/10356/148219
ISSN: 1521-3773
DOI: 10.1002/anie.202014781
Rights: This is the peer reviewed version of the following article: Teng, S., Chi, R. Y. & Zhou, S. J. (2021). Enantioselective three-component coupling of heteroarenes, cycloalkenes and propargylic acetates. Angewandte Chemie International Edition, 60(9), 4491-4495. https://dx.doi.org/10.1002/anie.202014781, which has been published in final form at https://doi.org/10.1002/anie.202014781. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
Fulltext Permission: open
Fulltext Availability: With Fulltext
Appears in Collections:SPMS Journal Articles

SCOPUSTM   
Citations 20

3
Updated on Dec 28, 2021

Page view(s)

118
Updated on May 15, 2022

Google ScholarTM

Check

Altmetric


Plumx

Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.