Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/148964
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dc.contributor.authorLin, Junquanen_US
dc.contributor.authorJo, Seung Binen_US
dc.contributor.authorKim, Tae-Hyunen_US
dc.contributor.authorKim, Hae-Wonen_US
dc.contributor.authorChew, Sing Yianen_US
dc.date.accessioned2021-06-03T07:53:04Z-
dc.date.available2021-06-03T07:53:04Z-
dc.date.issued2020-
dc.identifier.citationLin, J., Jo, S. B., Kim, T., Kim, H. & Chew, S. Y. (2020). RNA interference in glial cells for nerve injury treatment. Journal of Tissue Engineering, 11, 1-17. https://dx.doi.org/10.1177/2041731420939224en_US
dc.identifier.issn2041-7314en_US
dc.identifier.other0000-0001-6400-6100-
dc.identifier.other0000-0002-6084-5967-
dc.identifier.urihttps://hdl.handle.net/10356/148964-
dc.description.abstractDrivers of RNA interference are potent for manipulating gene and protein levels, which enable the restoration of dysregulated mRNA expression that is commonly associated with injuries and diseases. This review summarizes the potential of targeting neuroglial cells, using RNA interference, to treat nerve injuries sustained in the central nervous system. In addition, the various methods of delivering these RNA interference effectors will be discussed.en_US
dc.description.sponsorshipMinistry of Education (MOE)en_US
dc.description.sponsorshipMinistry of Health (MOH)en_US
dc.description.sponsorshipNational Medical Research Council (NMRC)en_US
dc.description.sponsorshipNational Research Foundation (NRF)en_US
dc.language.isoenen_US
dc.relationNMRC-CBRGen_US
dc.relationNMRC/CBRG/0096/2015en_US
dc.relationRG38/19en_US
dc.relation.ispartofJournal of Tissue Engineeringen_US
dc.rights© 2020 The Author(s). This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).en_US
dc.subjectEngineering::Bioengineeringen_US
dc.titleRNA interference in glial cells for nerve injury treatmenten_US
dc.typeJournal Articleen
dc.contributor.schoolSchool of Chemical and Biomedical Engineeringen_US
dc.contributor.schoolLee Kong Chian School of Medicine (LKCMedicine)en_US
dc.identifier.doi10.1177/2041731420939224-
dc.description.versionPublished versionen_US
dc.identifier.pmid32670539-
dc.identifier.scopus2-s2.0-85087475773-
dc.identifier.volume11en_US
dc.identifier.spage1en_US
dc.identifier.epage17en_US
dc.subject.keywordsRNA Interferenceen_US
dc.subject.keywordsCentral Nervous Systemen_US
dc.description.acknowledgementThe author(s) disclosed receipt of the following financial support for the research, authorship and/or publication of this article: SY Chew and J Lin would like to acknowledge partial funding support from the Singapore National Research Foundation under its National Medical Research Council Cooperative Basic Research Grant (NMRC-CBRG, NMRC/CBRG/0096/2015) and administered by the Singapore Ministry of Health’s National Medical Research Council; Ministry of Education Tier 1 grant (RG38/19). This research was supported in part by the National Research Foundation (NRF), Republic of Korea (2015K1A1A2032163, 2018K1A4A3A01064257, 2018R1A2B3003446).en_US
item.grantfulltextopen-
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