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https://hdl.handle.net/10356/149399
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DC Field | Value | Language |
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dc.contributor.author | Nieuwenhuijse, David F. | en_US |
dc.contributor.author | Oude Munnink, Bas B. | en_US |
dc.contributor.author | Phan, My V. T. | en_US |
dc.contributor.author | Munk, Patrick | en_US |
dc.contributor.author | Venkatakrishnan, Shweta | en_US |
dc.contributor.author | Aarestrup, Frank M. | en_US |
dc.contributor.author | Cotten, Matthew | en_US |
dc.contributor.author | Koopmans, Marion P. G. | en_US |
dc.contributor.author | Tay, Moon Yue Feng | en_US |
dc.contributor.author | Zuniga-Montanez, Rogelio | en_US |
dc.contributor.author | Wuertz, Stefan | en_US |
dc.date.accessioned | 2021-07-28T07:36:17Z | - |
dc.date.available | 2021-07-28T07:36:17Z | - |
dc.date.issued | 2020 | - |
dc.identifier.citation | Nieuwenhuijse, D. F., Oude Munnink, B. B., Phan, M. V. T., Munk, P., Venkatakrishnan, S., Aarestrup, F. M., Cotten, M., Koopmans, M. P. G., Tay, M. Y. F., Zuniga-Montanez, R. & Wuertz, S. (2020). Setting a baseline for global urban virome surveillance in sewage. Scientific Reports, 10(1). https://dx.doi.org/10.1038/s41598-020-69869-0 | en_US |
dc.identifier.issn | 2045-2322 | en_US |
dc.identifier.uri | https://hdl.handle.net/10356/149399 | - |
dc.description.abstract | The rapid development of megacities, and their growing connectedness across the world is becoming a distinct driver for emerging disease outbreaks. Early detection of unusual disease emergence and spread should therefore include such cities as part of risk-based surveillance. A catch-all metagenomic sequencing approach of urban sewage could potentially provide an unbiased insight into the dynamics of viral pathogens circulating in a community irrespective of access to care, a potential which already has been proven for the surveillance of poliovirus. Here, we present a detailed characterization of sewage viromes from a snapshot of 81 high density urban areas across the globe, including in-depth assessment of potential biases, as a proof of concept for catch-all viral pathogen surveillance. We show the ability to detect a wide range of viruses and geographical and seasonal differences for specific viral groups. Our findings offer a cross-sectional baseline for further research in viral surveillance from urban sewage samples and place previous studies in a global perspective. | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | Scientific Reports | en_US |
dc.rights | © 2020 The Author(s). This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. | en_US |
dc.subject | Engineering::Environmental engineering | en_US |
dc.title | Setting a baseline for global urban virome surveillance in sewage | en_US |
dc.type | Journal Article | en |
dc.contributor.research | Singapore Centre for Environmental Life Sciences and Engineering | en_US |
dc.contributor.research | Nanyang Technological University Food Technology Centre (NAFTEC) | en_US |
dc.identifier.doi | 10.1038/s41598-020-69869-0 | - |
dc.description.version | Published version | en_US |
dc.identifier.pmid | 32792677 | - |
dc.identifier.scopus | 2-s2.0-85089383261 | - |
dc.identifier.issue | 1 | en_US |
dc.identifier.volume | 10 | en_US |
dc.subject.keywords | Metagenomics | en_US |
dc.subject.keywords | Public Health | en_US |
item.fulltext | With Fulltext | - |
item.grantfulltext | open | - |
Appears in Collections: | SCELSE Journal Articles |
Files in This Item:
File | Description | Size | Format | |
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s41598-020-69869-0.pdf | 5.52 MB | Adobe PDF | View/Open |
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