Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/150224
Title: A facile synthesis of label-free carbon dots with unique selectivity-tunable characteristics for ferric ion detection and cellular imaging applications
Authors: Chan, Kok Ken
Yang, Chengbin
Chien, Yi-Hsin
Panwar, Nishtha
Yong, Ken-Tye
Keywords: Engineering::Electrical and electronic engineering
Issue Date: 2019
Source: Chan, K. K., Yang, C., Chien, Y., Panwar, N. & Yong, K. (2019). A facile synthesis of label-free carbon dots with unique selectivity-tunable characteristics for ferric ion detection and cellular imaging applications. New Journal of Chemistry, 43(12), 4734-4744. https://dx.doi.org/10.1039/C8NJ06306K
Journal: New Journal of Chemistry
Abstract: This work reports the synthesis of nitrogen and sulfur co-doped carbon dots (NS-CDs) via a one-step facile microwave-assisted pyrolysis using citric acid and thiourea as the carbon precursor and dopant, respectively. The resultant NS-CDs were found to be uniform in size and can be dispersed in aqueous solution. With an average size of 4.73 ± 0.65 nm, the NS-CDs exhibit excitation-dependent and pH-dependent photoluminescence properties in the visible range. Moreover, the NS-CDs also possessed a relatively high photoluminescence quantum yield of 28.9% and strong photostability in a high ionic strength environment. The NS-CDs were highly selective for Fe³⁺ detection in a water sample, achieving a limit of detection (LOD) of 0.16 μM. On top of this, the NS-CDs also demonstrated high detection sensitivity with a LOD of 0.17 μM and improved selectivity to Fe³⁺ in an acidic environment (pH 2). Specifically, the interference effect from Cu²⁺, Co²⁺, and Ag⁺ was lowered by 15%, 18%, and 64% respectively, highlighting an additional merit for the as-synthesized NS-CDs. This concept of pH tuning can be implemented to exploit the detection capability in both neutral and acidic environments to create specific analytical responses correlating to a specific targeted metal ion. Finally, we also demonstrated the versatility of the NS-CDs by employing them as a low-toxicity fluorescent label and for semi-quantitative Fe³⁺ sensing in cancer cells.
URI: https://hdl.handle.net/10356/150224
ISSN: 1144-0546
DOI: 10.1039/C8NJ06306K
Rights: © 2019 The Royal Society of Chemistry and the Centre National de la Recherche Scientifique. All rights reserved.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:EEE Journal Articles

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