Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/150711
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dc.contributor.authorLiu, Minen_US
dc.contributor.authorJia, Shenglanen_US
dc.contributor.authorDong, Tingen_US
dc.contributor.authorHan, Yuanen_US
dc.contributor.authorXue, Jingchuanen_US
dc.contributor.authorWanjaya, Elvy Rianien_US
dc.contributor.authorFang, Mingliangen_US
dc.date.accessioned2021-06-02T01:01:14Z-
dc.date.available2021-06-02T01:01:14Z-
dc.date.issued2019-
dc.identifier.citationLiu, M., Jia, S., Dong, T., Han, Y., Xue, J., Wanjaya, E. R. & Fang, M. (2019). The occurrence of bisphenol plasticizers in paired dust and urine samples and its association with oxidative stress. Chemosphere, 216, 472-478. https://dx.doi.org/10.1016/j.chemosphere.2018.10.090en_US
dc.identifier.issn0045-6535en_US
dc.identifier.urihttps://hdl.handle.net/10356/150711-
dc.description.abstractBisphenol A diglycidy ether (BADGE) and its derivatives are epoxy resins and widely used as emerging plasticizers in food packages and material coating. Though known as endocrine disruptors, little information is available on their occurrence, exposure routes and toxicity. Besides, the analysis of BADGE and its derivatives has always been a challenge due to their reactive chemical properties and the background contamination. Therefore, we firstly developed a novel water-free method to analyze BADGE and its derivatives in dust samples together with other two typical plasticizers bisphenol A (BPA) and bisphenol S (BPS). In order to investigate the levels in paired dust and urine samples, 33 paired samples were collected from Singapore. In both dust and urine samples, the predominant compounds were BPA, BADGE-2H2O and BPS. A significantly positive correlation of BPA levels in paired dust and urine samples was observed in this small-scale study. To tentatively explore the human health effect from exposure to these bisphenol plasticizers, we assessed the correlation between the urinary concentrations of these compounds and oxo-2’-deoxyguanosine (8-OHdG), an oxidative stress biomarker. The result showed that 8-OHdG levels in urine samples was positively correlated with urinary BPA level and body mass index (BMI), suggesting that elevated oxidative stress might be associated with BPA exposure and obesity. In the future, a larger scale study is warranted due to the limited sample size in this study.en_US
dc.description.sponsorshipBuilding and Construction Authority (BCA)en_US
dc.description.sponsorshipMinistry of Education (MOE)en_US
dc.description.sponsorshipNanyang Technological Universityen_US
dc.description.sponsorshipNational Environmental Agency (NEA)en_US
dc.language.isoenen_US
dc.relationM4011732.030en_US
dc.relationM4081915en_US
dc.relationM060030008en_US
dc.relationM4061617en_US
dc.relationM4062065en_US
dc.relation.ispartofChemosphereen_US
dc.rights© 2018 Elsevier Ltd. All rights reserved.en_US
dc.subjectEngineering::Environmental engineeringen_US
dc.titleThe occurrence of bisphenol plasticizers in paired dust and urine samples and its association with oxidative stressen_US
dc.typeJournal Articleen
dc.contributor.schoolSchool of Civil and Environmental Engineeringen_US
dc.contributor.researchNanyang Environment and Water Research Instituteen_US
dc.contributor.researchResidues and Resource Reclamation Centreen_US
dc.identifier.doi10.1016/j.chemosphere.2018.10.090-
dc.identifier.pmid30388685-
dc.identifier.scopus2-s2.0-85055699222-
dc.identifier.volume216en_US
dc.identifier.spage472en_US
dc.identifier.epage478en_US
dc.subject.keywordsTbisphenol A Diglycidyl Etheren_US
dc.subject.keywordsBisphenol Plasticizersen_US
dc.description.acknowledgementWe appreciate the contributions of all volunteers in this study. This work was funded by Singapore Ministry of Education Academic Research Fund Tier 1 (M4011732.030), Start-Up Grant of Nanyang Technological University (M4081915, M060030008), Singapore National Environment Agency (M4061617) and Singapore Building and Construction Authority (M4062065).en_US
item.fulltextNo Fulltext-
item.grantfulltextnone-
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