Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/150727
Title: A longitudinal study of choroidal changes following cataract surgery in patients with diabetes
Authors: Yip, Vivien Cherng-Hui
Laude, Augustinus
Tan, Kara Anne
Ding, Jianbin
Wong, Elizabeth
Agrawal, Rupesh
Keywords: Science::Medicine
Issue Date: 2019
Source: Yip, V. C., Laude, A., Tan, K. A., Ding, J., Wong, E. & Agrawal, R. (2019). A longitudinal study of choroidal changes following cataract surgery in patients with diabetes. Diabetes & Vascular Disease Research, 16(4), 369-377. https://dx.doi.org/10.1177/1479164119841536
Journal: Diabetes & Vascular Disease Research
Abstract: Objective: To study the structural changes in the choroid of diabetic patients following cataract surgery, using choroidal vascularity index and choroidal thickness. Methods: A prospective case–control study was conducted in 18 diabetic and 18 non-diabetic patients undergoing cataract surgery (phacoemulsification) in one eye. Enhanced depth imaging optical coherence tomography images were obtained before and after surgery. Niblack’s image binarization of images was performed to derive the choroidal vascularity index. Independent sample T-test compared the differences of choroidal vascularity index and choroidal thickness between diabetic and non-diabetic patients. Results: The baseline choroidal vascularity index was significantly lower in diabetic patients for both operated (mean difference vs non-diabetic: 0.0184, 95% CI: 0.004–0.0324, p=0.012) and non-operated (mean difference vs non-diabetic: 0.0145, 95% CI: 0.003–0.0256, p=0.012) eyes. Choroidal thickness increased following cataract surgery (diabetes: mean difference=12.4, 95% CI: 0.70–24.0, adjusted p=0.036; non-diabetic: mean difference=21.0, 95% CI: 4.39–37.6, adjusted p=0.011). Conclusion: Diabetic patients have reduced choroidal vascularity index than non-diabetic patients, suggestive of possible reduction in choroidal vascularity in diabetes. Choroidal thickness increased following cataract surgery in both diabetic and non-diabetic patients.
URI: https://hdl.handle.net/10356/150727
ISSN: 1479-1641
DOI: 10.1177/1479164119841536
Rights: © 2019 The Author(s). All rights reserved.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:LKCMedicine Journal Articles

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