Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/150739
Title: Thiazolidin-5-imine formation as a catalyst-free bioorthogonal reaction for protein and live cell labeling
Authors: Bi, Xiaobao
Yin, Juan
Rao, Chang
Balamkundu, Seetharamsing
Banerjee, Biplab
Zhang, Dingpeng
Zhang, Dawei
Dedon, Peter C.
Liu, Chuan-Fa
Keywords: Science::Biological sciences
Issue Date: 2018
Source: Bi, X., Yin, J., Rao, C., Balamkundu, S., Banerjee, B., Zhang, D., Zhang, D., Dedon, P. C. & Liu, C. (2018). Thiazolidin-5-imine formation as a catalyst-free bioorthogonal reaction for protein and live cell labeling. Organic Letters, 20(24), 7790-7793. https://dx.doi.org/10.1021/acs.orglett.8b03195
Project: ETPL-QP-19-06
NGF-2017-03-040
MOE 2016-T3-1-003
Journal: Organic Letters
Abstract: A previously undescribed reaction involving the formation of a thiazolidin-5-imine linkage was developed for bioconjugation. Being highly specific and operating in aqueous media, this simple condensation reaction is used to chemoselectively label peptides, proteins, and living cells under physiological conditions without the need to use toxic catalysts or reducing reagents.
URI: https://hdl.handle.net/10356/150739
ISSN: 1523-7060
DOI: 10.1021/acs.orglett.8b03195
Rights: © 2018 American Chemical Society. All rights reserved.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:SBS Journal Articles

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