Please use this identifier to cite or link to this item: https://hdl.handle.net/10356/150988
Title: Micromotor-assisted human serum glucose biosensing
Authors: Kong, Lei
Rohaizad, Nasuha
Muhammad Zafir Mohamad Nasir
Guan, Jianguo
Pumera, Martin
Keywords: Science::Chemistry
Issue Date: 2019
Source: Kong, L., Rohaizad, N., Muhammad Zafir Mohamad Nasir, Guan, J. & Pumera, M. (2019). Micromotor-assisted human serum glucose biosensing. Analytical Chemistry, 91(9), 5660-5666. https://dx.doi.org/10.1021/acs.analchem.8b05464
Project: SERC A1783c0005
Journal: Analytical Chemistry 
Abstract: Artificial self-propelled micromachines have shown great promise in biomedical sciences. In this work, we use Mg/Pt Janus micromotors with self-rejuvenating surfaces to enhance the electrochemical sensing performance and sensitivity toward glucose in human serum. The detection of glucose is based on the glucose oxidase enzyme and ferrocenemethanol shuttle system, where mass transfer was dramatically enhanced by the rapid motion of Mg/Pt Janus micromotors. The obtained chronoamperometric data show that Mg/Pt Janus micromotors play a synergistic role in enhancing the current response at millimolar concentrations of glucose in human serum. The current signals increased with the corresponding increase in amount of micromotors introduced. Furthermore, a linear relationship between current signal and glucose concentration was established, while the limit of detection improved when mobile Mg/Pt Janus micromachines were used. Glucose detection enhanced by micromachines may pave the way for their future applications in biomedicine and medical diagnostic devices.
URI: https://hdl.handle.net/10356/150988
ISSN: 0003-2700
DOI: 10.1021/acs.analchem.8b05464
Rights: © 2019 American Chemical Society. All rights reserved.
Fulltext Permission: none
Fulltext Availability: No Fulltext
Appears in Collections:IGS Journal Articles
SPMS Journal Articles

SCOPUSTM   
Citations 10

28
Updated on Jun 23, 2021

PublonsTM
Citations 10

26
Updated on Jun 23, 2021

Page view(s)

57
Updated on Sep 23, 2021

Google ScholarTM

Check

Altmetric


Plumx

Items in DR-NTU are protected by copyright, with all rights reserved, unless otherwise indicated.