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dc.contributor.authorShi, Yuzhien_US
dc.contributor.authorLi, Zhenyuen_US
dc.contributor.authorLiu, Patricia Yangen_US
dc.contributor.authorNguyen, Binh Thi Thanhen_US
dc.contributor.authorWu, Wenshuaien_US
dc.contributor.authorZhao, Qianbinen_US
dc.contributor.authorChin, Lip Keten_US
dc.contributor.authorYap, Peng Huaten_US
dc.contributor.authorZhou, Xiaohongen_US
dc.contributor.authorZhao, Hongweien_US
dc.contributor.authorYu, Danen_US
dc.contributor.authorTsai, Din Pingen_US
dc.contributor.authorLiu, Ai Qunen_US
dc.identifier.citationShi, Y., Li, Z., Liu, P. Y., Nguyen, B. T. T., Wu, W., Zhao, Q., Chin, L. K., Yap, P. H., Zhou, X., Zhao, H., Yu, D., Tsai, D. P. & Liu, A. Q. (2021). On-chip optical detection of viruses : a review. Advanced Photonics Research, 2(4), 2000150-.
dc.description.abstractThe current outbreak of the coronavirus disease-19 (COVID-19) pandemic worldwide has caused millions of fatalities and imposed a severe impact on our daily lives. Thus, the global healthcare system urgently calls for rapid, affordable, and reliable detection toolkits. Although the gold-standard nucleic acid amplification tests have been widely accepted and utilized, they are time-consuming and labor-intensive, which exceedingly hinder the mass detection in low-income populations, especially in developing countries. Recently, due to the blooming development of photonics, various optical chips have been developed to detect single viruses with the advantages of fast, label-free, affordable, and point of care deployment. Herein, optical approaches especially in three perspectives, e.g., flow-free optical methods, optofluidics, and surface-modification-assisted approaches, are summarized. The future development of on-chip optical-detection methods in the wave of emerging new ideas in nanophotonics is also briefly discussed.en_US
dc.relation.ispartofAdvanced Photonics Researchen_US
dc.rights© 2021 The Authors. Advanced Photonics Research published by Wiley- VCH GmbH. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.en_US
dc.titleOn-chip optical detection of viruses : a reviewen_US
dc.typeJournal Articleen
dc.contributor.schoolSchool of Electrical and Electronic Engineeringen_US
dc.contributor.schoolLee Kong Chian School of Medicine (LKCMedicine)en_US
dc.contributor.researchCentre for Bio Devices and Signal Analysis (VALENS)en_US
dc.description.versionPublished versionen_US
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